Adenosine is a purine nucleoside which is an effective controller of inflammation. The inflammatory effect of adenosine is expressed via its four receptor subtypes viz. A1, A2A, A2B and A3. The various inflammatory conditions including rheumatoid arthritis (RA) are initiated by adenosine receptors of which A2A and A3 play a vital role. RA primarily is an auto-immune disorder which is manifested as chronic inflammation in the synovial lining of joints. In order to develop an effective treatment, the role of cytokines, IL–1, TNF-α and IL–6 is crucial. Besides, the knowledge of PI3K-PKB/Akt and NF-kB signaling pathway is also important to understand the antiinflammatory targets. Methotrexate along with various other molecules like, NSAIDs and DMARDs are presently used as treatment lines for controlling RA. The enhanced knowledge of the preclinical stages and pathogenesis along with recent potent therapeutics raises the hopes that RA can be prevented in the near future.
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Background: A large number of cosmetic formulations have been developed based on herbs. Indian women have been using herbs such as sandalwood, aloe for skincare protection, since ages. In India, the rich cultural heritage is behind the materials used in cosmetics from the earliest period of medical and cosmetic art. Objective: Continuous application of synthetic compounds on the skin causes many adverse effects such as skin irritation, allergy, discoloration, rashes along with skin cancer. The aim of this review article is to explore herbs for different skincare needs. Materials and Methods: A literature search was done on various herbs used for skin nourishment, cleansing, sun-screens, bleach, anti-ageing, moisturization and other skin requirements. Results: There are various herbs present in nature. They improve and clarify skin gently in an utmost manner. Conclusion: These herbs are full of phytoconstituents, having natural goodness to fulfill the different demands of skin.
Background: Dandruff is a major problem of hair, which cannot be fully cured with the aid of chemicals. An attempt has been made to prepare a poly-herbal anti-dandruff hair care formulation and it is standardized to ensure its stability and quality aspects. Objective: The present work is oriented at the synthesis of herbal anti-dandruff hair formulation and the estimation of its various aspects for its valuability. Materials and Methods: The herbal preparation was prepared in the laboratory, on the basis of decided proportion, with the help of all the herbal contents. The pack was gauged for its various parameters. Results: The results were concluded to be sufficiently ample for the assessment of herbal formulation. The findings of different aspects vindicated the worth of the formulation. Conclusion: Herbal hair formulation has been formulated and assessed using the various aspects. It serves as a good alternate, devoid of any side effects. The results can be unified while evolving the pharmacopoeial standards.
Background: Postpartum is an important phase of life after childbirth. It needs to be highly important as in terms of health in future life. This time brings lots of complications with it. Lots of aspects need to be looked after as the care of the new mom is essential to bring back her stamina and strength. Objective: The objective of this review article is to explore the heeding power hidden in nature for returning back to the mothers to the pre-pregnancy state. There are various areas of concern after postpartum to heal up the body overall, such as to heal up the uterus, providing galactagogues, nutritives, maintenance of hormones and restoring back the strength and tone of the abdomen. Materials and Methods: A literature search has been done on the various herbs, which fulfill the various desired aspects to be looked after post pregnancy. Results: There are various herbs present in nature, regarding their hidden potential still the awareness is not up to the mark. This review highlights the various plants which have been proven to be useful in dealing the post-pregnancy issues. They deal with all the aspects of complications and issues occurring post pregnancy. They heal the uterus which has undergone so many types of changes, maintains the balance of hormones back, besides providing nutrition and increasing the production of milk, they also restore back the tone and strength of the walls of the abdomen. Conclusion: These herbs are full-fledged with the phytoconstituents that heal the whole system after delivery. The need of present time is to take patiently these as the source of medicines regularly under medical supervision to overcome the various concerned problems of post pregnancy.
Background:Herbal based hair dyes are being preferred on large scale, due to the vast number of advantages it exerts to overcome the ill-effects of a chemical based hair dye. We have attempted to prepare and standardize this preparation to ensure its quality as well as stability aspects.Objective:The current research was aimed at the preparation of herbal hair dye and the evaluation of its various parameters as organoleptic, physico-chemical, phytoconstituents, rheological aspects, patch test and stability testing for its efficacy and shelf life.Materials and Methods:The herbal dye was prepared in-house according to the proposed composition, using all the natural ingredients. The dye was evaluated for its organoleptic, physico-chemical and stability parameters.Results:The parameters were found to be comparable and sufficient for the evaluation of herbal dye. The values of different evaluations justified the usage of the hair dye.Conclusion:Herbal based hair dye has been prepared and evaluated using the various parameters. It offers a natural alternate, which can be used, irrespective of any side effects. The results can be incorporated while developing the pharmacopoeial standards.
Background:Herbs are the most trending taste enhancers, carrying multiple benefits. Sprinkling them in minute amounts in pasta, salads, sautéed vegetables, curries, fried rice or adding them in dips and sauces can lead to enhanced flavours. The fresh and dried versions serve the same purpose, especially when the fresh ones are not available. Objective:The objective of this article is to explore and review trending flavouring herbs of the present era with reference to the knowledge available from previous texts. Materials and Methods:A literature review has been performed on various herbs such as dill, cilantro, parsley, chives, mint, oregano, etc, which can be used as healthy and taste enhancing sprinklers and garnishers for foods. Results:There are various herbs present in nature in many forms and patterns, some provide anti-inflammatory benefits, are anti-microbial and most of them are digestive in nature. Conclusion:These herbs are very rich in phytoconstituents, having multiple properties like anti-oxidant and carminative effects. They are superior as compared to artificial additives as well.
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