Given the outbreak of COVID-19 pandemic and the shortage of medical resource, extensive deep learning models have been proposed for automatic COVID-19 diagnosis, based on 3D computed tomography (CT) scans. However, the existing models independently process the 3D lesion segmentation and disease classification, ignoring the inherent correlation between these two tasks. In this paper, we propose a joint deep learning model of 3D lesion segmentation and classification for diagnosing COVID-19, called DeepSC-COVID, as the first attempt in this direction. Specifically, we establish a large-scale CT database containing 1,805 3D CT scans with fine-grained lesion annotations, and reveal 4 findings about lesion difference between COVID-19 and community acquired pneumonia (CAP). Inspired by our findings, DeepSC-COVID is designed with 3 subnets: a cross-task feature subnet for feature extraction, a 3D lesion subnet for lesion segmentation, and a classification subnet for disease diagnosis. Besides, the task-aware loss is proposed for learning the task interaction across the 3D lesion and classification subnets. Different from all existing models for COVID-19 diagnosis, our model is interpretable with fine-grained 3D lesion distribution. Finally, extensive experimental results show that the joint learning framework in our model significantly improves the performance of 3D lesion segmentation and disease classification in both efficiency and efficacy.
A double sensing with selective bitline voltage regulation (DS-SBVR) scheme is proposed to improve the throughput of ultralow-voltage static random access memory (SRAM). It senses the bitline voltage swing twice and compares two samples for confirmation. The bitline voltage is dynamically regulated by charge sharing between two sensing steps. Different from other timing speculative SRAMs, its error flag is generated much earlier; therefore, it achieves a higher reading throughput. Meanwhile, a digitized timing scheme is proposed to generate configurable timing pulses for the DS-SBVR. Compared with other timing techniques, it has a better ability to process, voltage, temperature (PVT) tracking and variance suppression. For fair comparison of performance/power/area, three different columnbased timing speculative designs are implemented in the same technology. A 28-nm test chip including 40 SRAM macros (128 × 32) is fabricated to demonstrate the scheme. Compared with the conventional design, measurements show that DS-SBVR achieves 1.45× throughput gain at 0.6-V SS corner. The figure of merit (FOM) is introduced for power, performance, and area (PPA) gain comparison. Compared with the conventional design, the FOMs of PPA gain are 1.54 and 2.33 in 128-row and 512-row memories, respectively. Compared with other timing speculative SRAMs, it achieves 1.83×-2.24× improvement.
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