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Nurses should shoulder the responsibility to increase patients' intention to receive examination of diabetes complications. The results of this study can be used to promote nurses' care efficacy in preventing diabetes complications. They can also provide medical institutions with information to establish prevention and control policies for diabetes complications.

This study employed a comprehensive systematic review of the literature (SRL) process with the Content Analysis Toolkits for Academic Research (CATAR) for conducting a bibliometric analysis of the 2814 general SDG-related papers and 92 review papers selected from the Web of Science database from 2013 to 2022. The overview analysis found that the US and UK took the lead in publication and citation. The WHO and several universities were identified as the most prominent institutes around the globe. The field distribution of the most cited papers revealed the existence of a “strong sustainability” paradigm and the importance of science and technology. A landscape of 1123 papers was included in eight clusters according to the bibliographic coupling algorithms in the Multi-stage Document Clustering (MSDC) process. These clusters were then categorized into three groups, “synergies and trade-offs”, “networking”, and “systems analysis”, demonstrated in the theme maps. As for the 92 SDG-related review papers, most were shaped based on literature analysis without specified countries. Moreover, SDG 3 was identified as that exclusively studied in most papers. The information presented is expected to help research scholars, public sectors, and practitioners monitor, gather, check, analyze, and use the growing volume of SDG-related academic articles.

Combined hepatocellular cholangiocarcinoma (cHCC-CC) is a rare subtype of primary liver malignancy characterized by aggressive behavior and poor prognosis. Radial surgical resection is the standard curative treatment. However, effective therapeutic options for recurrent or metastatic cHCC-CC are still lacking, mainly because of an insufficient understanding of the molecular and genomic alterations of cHCC-CC, preventing the discovery of specialized targeting therapy. Here, we present the case of a patient with metastatic cHCC-CC on first-line treatment of gemcitabine, cisplatin, and nab-paclitaxel. A comprehensive genomic profile revealed four clinically relevant single nucleotide variants ( BRCA2, PIK3C2G, RET , and TP53 ), two amplified genomic regions ( CRKL and MAPK1 ), and 11 heterozygous genomic deletions ( BAP1, CDKN2A, PTCH1, TSC1, BRCA2, RB1, RAD51, PALB2, TSC2, SMAD4 , and STK11) . The patient underwent olaparib treatment and achieved a remarkable and sustained tumor response. Our experience indicates that BRCA2 mutations could be a potential therapeutic target for patients with cHCC-CC.

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