The current study confirmed that long-term NNK exposure plays a role in HNSCC by increasing anti-apoptosis and therapeutic resistance via the Snail-RKIP signaling pathway. Our data also suggest that α7 nicotinic acetylcholine receptor (α7-nAChR) inhibition or targeting Snail may provide a feasible rationale for preventing the progression of HNSCC.
The study examined the effects of swimming pools on healthcare professionals' willingness to engage in recreational activities, physical anxiety, and physical and mental well-being in the context of COVID-19. The research adopted the mixed research method, used SPSS 26.0 statistical software to test the reliability of the questionnaire, and then collected 840 valid questionnaires; first analyzed the data with basic statistics, t-test, ANOVA, and PPMCC test methods, and then used the interview method to collect expert opinions. A multi-check approach assembled all data and discussions. The study found that the use of personnel dynamic tracking systems or measures, combined with sodium hypochlorite and repeated filtration to stabilize water quality, could maintain the confidence of most medical workers in the swimming pool sports environment for epidemic prevention and avoid violations. The government could formulate safety prevention and control mechanisms in traffic and establish appropriate traffic routes. Next, formulated a prescription for swimming or other physical activity mechanisms for men aged 31–50 and redesigned measures for medical staff over 51 years old to have tense head issues and physical fatigue, promote blood circulation and improve sleep quality. This will promote the purpose of relieving stress and regulating the physical and mental health of medical staff after engaging in swimming.
The purpose of the research is to analyze the improvement in the physical and mental health of college students after intermittent exercises are performed by massage. The present study employed a mixed research method. An experimental study was conducted to analyze the current status of the volunteers’ sports performance and body composition, and then a questionnaire was designed for the subjects’ physical and mental health. The data were then analyzed using SPSS 26.0 software for statistical analysis such as t-test and ANOVA. The subjects were then interviewed to collect their opinions on the study results, and finally, the results were explored by multivariate analysis. The study found that intermittent exercise can help university students develop physical fitness and performance, improve body composition, and regulate physical and mental health. The combination of intermittent exercise with sports massages further enhanced the performance of sit-ups and standing long jump, improve blood pressure, BMI, and self-confidence, as well as reducing suicidal tendencies (experimental group > control group). However, intermittent exercise participants still experienced fatigue, headache, emotional loss, and fear of depression, and the addition of sports massage did not significantly improve flexibility and cardiorespiratory endurance (control group > experimental group).
This study aims to analyze the impact of attractiveness, satisfaction, and willingness to revisit in the perception of cultural tourism tourists and whether cultural tourism could be a remedy to revitalize rural economic development under the epidemic, using the Hakka settlement in Hukeng town as a case study. In this study, a mixed research method is applied to collect 670 questionnaires by snowball sampling and used SPSS 26.0 statistical software to conduct basic statistical validation and Pearson product-moment correlation coefficient (PPMCC) validation; the semi-structured is also used semi-structured interviews to collect the opinions of six experts and scholars, and the final results were examined by multivariate validation. The researchers found the following dimensions to be attractive for tourists to experience cultural tourism: rural scenery, heritage museums and cultural goods, low spending, use of media marketing, planning for proper tourism information, and public transportation construction effectiveness. However, there is also a need to improve the current situation of rural tourism transportation and transportation facilities, inject young development manpower, improve the knowledge and skills of the elderly to start their businesses, develop business opportunities, and stabilize prices, and improve the quality and satisfaction of tourists to promote the desire to travel. The higher the attractiveness, the higher the satisfaction, and the stronger the willingness to revisit.
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