TDI-derived right ventricular IVA may be used as an adjunctive, reliable, noninvasive parameter for the early detection of right ventricular systolic dysfunction in patients with MS but without signs of systemic venous congestion.

The combination of IVC diameter and collapsibility index is a simple a semiquantitative approach that might provide a better estimation of RAP.

bstructive sleep apnea (OSA) is common, underdiagnosed and associated with cardiovascular diseases such as heart failure, left ventricular (LV) and right ventricular (RV) dysfunction, myocardial infarction, arrhythmias, and systemic and pulmonary hypertension. 1 Previous studies have shown the adverse affects of OSA on both LV and RV functions. 2,3 However, many risk factors for OSA, such as excess weight, male sex and advanced age, are the same as the risk factors for cardiovascular diseases. Proving that OSA actually causes cardiac dysfunction independent of these confounding risk factors is difficult. Early recognition of RV dysfunction before pulmonary arterial (PA) hypertension develops is important for preventing further progression to heart failure and even death. 4 Thus, there is a need for a more detailed analysis of its pathophysiologic importance and for techniques that may supplement available technology in identifying early signs of RV impairment. Editorial p 250Recently, tissue Doppler imaging (TDI) and strain/strain rate (SR) imaging have been shown to be reliable and accurate novel techniques for evaluating global and regional ventricular function. 5 As TDI has the disadvantage of being preload and afterload dependent, a new TDI-derived index of isovolumic myocardial acceleration (IVA) has been validated to be a reliable and relatively load independent measure of cardiac systolic function. 6 Velocity vector imaging (VVI) is a novel method based on 2-dimensional B-mode images. The method involves tracking ultrasonic speckles permitting angle-independent measurement of tissue velocity and deformation. 7 It has been shown to be a reliable method for the quantification of regional contractile dysfunction with the ability to detect subclinical cardiac dysfunction. 8 In this study, VVI and TDI were used to evaluate regional subclinical RV dysfunction in newly diagnosed moderate-to-severe OSA The aims of this study were to evaluate subclinical regional right ventricular (RV) dysfunction in newly diagnosed obstructive sleep apnea (OSA) patients without systemic and pulmonary arterial (PA) hypertension, and to correlate OSA severity to RV dysfunction, using both velocity vector imaging (VVI)-derived strain imaging and tissue Doppler imaging (TDI).

Background:The aim of the present study was to evaluate pre-existent subclinical mechanical atrial dysfunction in patients with postoperative atrial fibrillation (POAF) by using novel echocardiographic techniques. Methods and Results:Ninety-six patients with sinus rhythm, undergoing coronary artery bypass graft (CABG) operation were prospectively enrolled. Preoperative left atrial (LA) reservoir, conduit and booster functions were evaluated by 3 different methods: conventional echocardiography, tissue Doppler imaging (TDI), and 2-dimensional strain imaging based-velocity vector imaging (VVI). POAF occurred in 25 out of 96 patients (26%). LA volume index (LAVI) was the only conventional parameter associated with POAF. TDI-derived LA velocities were similar in study groups. In VVI analysis, LA systolic strain, strain rate (SRs) and early diastolic strain rate (ESRd) were impaired in patients who developed POAF after CABG (P=0.0001). Age, LAVI, LA peak systolic strain, SRs and ESRd were found to be the independent predictors of POAF. The optimal cut-off point of 44.0% (88.7% sensitivity, 96% specificity) for LA strain, 1.7 s -1 (88% sensitivity, 86.2% specificity) for SRs and 1.95 s -1 (sensitivity 72%, 70.4% specificity) for ESRd predicted POAF in this study.Conclusions: VVI-derived strain imaging could be used as an adjunctive non-invasive method for evaluating subclinical atrial mechanical dysfunction in patients undergoing CABG. This might help us to identify patients with high risk of POAF in clinical practice. (Circ J 2010; 74: 2109 - 2117

VVI- derived strain imaging and TDI-derived IVA may be used as adjunctive, reliable, noninvasive parameters for evaluating subclinical ventricular dysfunction in patients with chronic, severe AR. This may help to identify patients for closer follow-up and to determine the need for surgery before developing irreversible, severe heart failure.

TDI-derived RV IVA is a novel, noninvasive echocardiographic index which may be used in the assessment of subclinical RV dysfunction in patients with COPD.

The results of our study show no changes in the RV functions in obese and overweight who were otherwise healthy subjects. We also revealed a significant correlation between BMI and left ventricular diameters and wall thickness but no relation with RV diameters or functions.

No abstract