Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg.
Atopic dermatitis — is a chronic disease, with immune mechanisms leading to high level of immunoglobulin Е and abnormal skin reactivity. The current review is presenting the experimental and clinical study results regarding to Т-regulatory cells participation in atopic dermatitis immune response.
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