In order to estimate the best affinity of rosemary extract towards the removal of triacylglycerol (TAG) from a real human serum albumin sample HSA in vitro, Rosemary leaves were obtained from Rosmarinus officinalis L plant, and rosemary extracts were prepared with four well selected ethanol-water concentrations combinations and were screened accordingly. The relative affinities of the rosemary (RM) extracts using the selected extraction solvents were evaluated spectrophotometrically and analyzed by applying a well-defined standard equation for each extract. Our results of the current study suggest that the extracts of RM plant could be considered as effective agents to remove TAG from human serum albumin in vitro. The relative affinity is dependent on the concentration of ethanol -water ratio used in the extraction procedure. The relative affinities of plant extracts in this study towards the removal of TAG showed different extends for TAG removal and were varied from 3.96 to 11.16 dependent on ethanol -water ratio. The studied extracts interacted with human serum albumin (HSA) with different binding affinities, which were directly related to their relative affinities to remove TAG from the human serum albumin sample. The present study clearly shows that the highest relative affinity was observed in 50% ethanol -water extracting solution.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.