The characteristics of large bowel cancer in young Egyptian patients do not differ significantly from those in older patients. Despite the high incidence of large bowel cancer in young Egyptian patients, family history and pathologic features of tumors do not support a hereditary origin of colorectal cancer in this age group in Egypt.

No abstract

The combined abdomino-perineal approach is useful to complete rectal resection in a highly selected group of patients with technically difficult low rectal pathologies. The technique is probably safe in cancer patients and new indications are evolving. Expectations for preservation of continence are disappointing.

To assess the advantage of using intraoperative endoscopic guidance during sleeve gastrectomy and its efficiency to decrease various complications.Methods: This was a retrospective study at Ain shams specialized hospital and Cure hospital. Patients who had sleeve gastrectomy with intra-operative endoscopic guidance were included in this study.Results: From September 2017 to February 2019, 226 patients had LSG as a definitive bariatric procedure. All the procedures were done with intra-operative endoscopic guidance. Seventy nine percent were female with a mean age of 39.7±14 years (range 23-49 years) and a mean body mass index of 48.6±14 kg/m2 (range 41-59 kg/m2 ). Two cases showed intraoperative leak that was managed intraoperatively by over suturing and omental patch. One case showed mild twisting at the incisura angularies that was managed intraoperatively by fixing the twisted angle to the retroperitoneum. Marked internal bleeding from the staple line was seen in two cases; which necessitated endoscopic clip insertion in one case and epinephrine injection for the other. The average length of the hospital stay was 1.8 days post operatively. The post-operative leakage was 0% and no cases had obstructive symptoms. Conclusion:Sleeve gastrectomy surgery with endoscopic guidance is very important not only to calibrate the size of the gastric pouch instead of the bougie, but also to prevent various complications as gastric obstruction or bleeding or even fatal complications as gastric leak.

Background: Integration of neoadjuvant chemotherapy (NCT) in early 70s resulted that many LABC tumors become resectable but with total mastectomy especially those with partial response, oncoplastic techniques give better oncological outcome with better cosmetic results. Objective: We evaluate the oncological safety of oncoplastic breast surgery (OS) in LABC showing partial response to NCT. Methods: We prospectively analyzed the data of 32 out of 58 patients with LABC who showed partial response to NCT and could have conservative surgery with advanced oncoplastic techniques rather than total mastectomy. Results: Out of 58 patients with LABC, received neoadjuvant chemotherapy, complete response was observed in 8 patients (13%), partial response reported in 32 (55.1%) cases, 12 patients (20%) had stable disease and 6 patients (10%) showed progressive disease. Data of 32 cases were studied (mean age 44.84 ± 9.10 years; range 26 -59 years). Inferior pedicle was performed in 9 cases, mini LD flap in 3 patients, 5 had Grissotti technique, 6 with superomedial pedicle, 4 had V mammoplasty and 3 with J mammoplasty and 2 had vertical mammoplasty. Margins were positive in 5 cases (15.6%) with mean margin width 9.63 ± 5.72 (range 0 -22 mm), and the local recurrence was reported in 2 cases (6.2%). Complications were reported in 3 cases (9.3%). The follow up was 1.67 ± 1.03 (range 0 -3.3 years). Conclusions: Integration of neoadjuvant chemotherapy together with advanced oncoplastic techniques opens a new way for management of LABC especially those showing partial response with avoidance of total mastectomy, and comparable oncological safety in addition to better aesthetic and psychological outcome.