BackgroundThe aging of Chinese society has increased interest in improving the health-related quality of life (HRQoL) of the elderly, including their oral health-related quality of life (OHRQoL). This study aims to evaluate the OHRQoL of elders living in Sichuan Province (China) and to explore the explanatory factors of their OHRQoL.MethodsA cross-sectional study conducted in 2016 in the Sichuan Province analyzed data from 744 elders, aged 65 to 74 years (mean age 69.3, 51.3% female). Clinical examinations and questionnaires were completed to collect information on the participants’ socio-demographic characteristics, health-related behaviors, dental status, subjective health conditions and General Oral Health Assessment Index (GOHAI) score.ResultsThe mean GOHAI score was 48.23 (SD 7.62), and the median score was 49. After adjustment for age and gender, the multiple linear regression analysis showed that participants who were female, had fair or poor self-rated oral health, decayed, missing and filled teeth (DMFT) score ≥ 20, fair or poor self-rated general health, and ≥ 2 teeth with root caries had worse OHRQoL, and participants who were edentulous had better OHRQoL (F = 29.58, p < 0.001).ConclusionThe OHRQoL of the elders living in Sichuan Province was relatively good. The explanatory variables were gender; self-rated oral health; DMFT score; self-rated general health; number of natural teeth; and number of teeth with root caries. More attention should be paid to caries status and retention of healthy teeth to improve the OHRQoL of elders in Sichuan Province, preserving a healthy mouth contributes to better OHRQoL.
Background: This in vitro study aimed to assess the ability and efficacy of HX-BGC, a novel bioactive glass-ceramic (SiO 2 -P 2 O 5 -CaO-Na 2 O-SrO), to reduce dentine tubule permeability. Methods: Dentine discs from human third molars were etched and randomly allocated into five groups: Group 1 -distilled water; Group 2 -Sensodyne Repair toothpaste (containing NovaMin®); Group 3 -HX-BGC toothpaste (containing 7.5% HX-BGC); Group 4 -control toothpaste (without HX-BGC); and Group 5 -HX-BGC powder. Specimens were treated daily by brushing with an electric toothbrush for 20 seconds. Between daily treatments (7 days total), specimens were immersed in artificial saliva for 24 hours. Dentine permeability was measured at baseline, after the first treatment, after the first 24-hour immersion in artificial saliva and at the end of day 7. Dentine morphology and surface deposits were observed by scanning electron microscopy after one day and 7 days of treatment, respectively. Results: Sensodyne Repair and bioactive glass-ceramic toothpaste significantly and immediately lowered dentine permeability. The HX-BGC powder group showed the highest reduction in dentine permeability after 7 days of treatment. Conclusions: The novel bioactive glass-ceramic material HX-BGC is effective in reducing dentine permeability by occluding open dentine tubules, indicating that HX-BGC may be a potential treatment for dentine hypersensitivity.
Issues caused by maxillofacial tumours involve not only dealing with tumours but also repairing jaw bone defects. In traditional tumour therapy, the systemic toxicity of chemotherapeutic drugs, invasive surgical resection, intractable tumour recurrence, and metastasis are major threats to the patients’ lives in the clinic. Fortunately, biomaterial-based intervention can improve the efficiency of tumour treatment and decrease the possibility of recurrence and metastasis, suggesting new promising antitumour therapies. In addition, maxillofacial bone tissue defects caused by tumours and their treatment can negatively affect the physiological and psychological health of patients, and investment in treatment can result in a multitude of burdens to society. Biomaterials are promising options because they have good biocompatibility and bioactive properties for stimulation of bone regeneration. More interestingly, an integrated material regimen that combines tumour therapy with bone repair is a promising treatment option. Herein, we summarized traditional and biomaterial-mediated maxillofacial tumour treatments and analysed biomaterials for bone defect repair. Furthermore, we proposed a promising and superior design of dual-functional biomaterials for simultaneous tumour therapy and bone regeneration to provide a new strategy for managing maxillofacial tumours and improve the quality of life of patients in the future.
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