Abstract. Post-Welding Heat Treatment (PWHT) is usually taken after welding and joining of vessel steel, which effects the mechanical and Hydrogen Induced Cracking (HIC) resistance property of vessel plates. Simulating PWHT experiment was taken to research on the effect on mechanical property and HIC-resistance of PWHT of vessel plates. Some conclusions can be summarized as following. Comparing with the normalizing samples, the tensile strength of the samples after PWHT with holding time of 2h, 6h and 20h decreases by 27MPa, 44MPa and 47MPa. Ductile Brittle Transition Temperature (DBTT) of the normalizing samples was almost close to those of the samples after PWHT. But the impact energy of samples at 0℃ increased with rise of PWHT holding time. And the hardness of samples decreases with rise of PWHT holding time. As shown in morphology structure, the precipitation of carbonide increases with the rise of holding time of PWHT, which decreases the strength and hardness of samples and raises the impact energy. But PWHT has a little effect on HIC-Resistance, which means PWHT don't deteriorate property of HIC-Resistance of vessel plates severely.
JOURNAL/nrgr/04.03/01300535-202403000-00034/inline-graphic1/v/2023-08-11T153926Z/r/image-tiff
Diabetic peripheral neuropathy is a common complication of diabetes mellitus. Elucidating the pathophysiological metabolic mechanism impels the generation of ideal therapies. However, existing limited treatments for diabetic peripheral neuropathy expose the urgent need for cell metabolism research. Given the lack of comprehensive understanding of energy metabolism changes and related signaling pathways in diabetic peripheral neuropathy, it is essential to explore energy changes and metabolic changes in diabetic peripheral neuropathy to develop suitable treatment methods. This review summarizes the pathophysiological mechanism of diabetic peripheral neuropathy from the perspective of cellular metabolism and the specific interventions for different metabolic pathways to develop effective treatment methods. Various metabolic mechanisms (e.g., polyol, hexosamine, protein kinase C pathway) are associated with diabetic peripheral neuropathy, and researchers are looking for more effective treatments through these pathways.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.