Developing anodes with a high and stable energy density for both gravimetric and volumetric storage is vital for high-performance lithium/sodium-ion batteries. Herein, an SnSe/few-layered graphene (FLG) composite with a high tap density (2.3 g cm −3 ) is synthesized via the plasma-milling method, in which SnSe nanoparticles are strongly bound with the FLG matrix, owing to both Sn−C and Se−C bonds, to form nanosized primary particles and then assemble to microsized secondary granules. The FLG can effectively alleviate the large stress generated from the volume expansion of SnSe during cycling based on its superstrength. Furthermore, as demonstrated by the density-functional theory calculations, the Sn−C and Se−C co-bonding benefitting from the formation of substantial vacancy defects on the P-milling-synthesized FLG enables strong affinity between SnSe nanoparticles and the FLG matrix, preventing SnSe from aggregating and detaching even after long-term cycling. As an anode for lithium-ion batteries, it exhibits high gravimetric and volumetric capacities (864.8 mAh g −1 and 1990 mAh cm −3 at 0.2 A g −1 ), a high rate (612.6 mAh g −1 even at 5.0 A g −1 ), and the longest life among the reported SnSe-based anodes (capacity retention of 92.8% after 2000 cycles at 1.0 A g −1 ). Subsequently, an impressive cyclic life (capacity retention of 91.6% after 1000 cycles at 1.0 A g −1 ) is also achieved for sodium-ion batteries. Therefore, the SnSe/FLG composite is a promising anode for high-performance lithium/sodium-ion batteries.
There were 146 patients with a median age of 4.6 years (range, 0.18-17.1 years), 46.6% were male, 80.8% were light skin colored, and 15.7% were younger than 2 years. The first-attempt success rates were 75% (95% CI, 63.8-84.2%) using AV300 and 73% (95% CI, 61.9-81.9%) using the standard method (P = 0.85). Patients with dark or medium skin color were 0.38 times less likely to have a successful first attempt than patients with light skin color. The difference between the two treatment groups in number of skin punctures and the time to insertion was not significant. Although the AV300 was easy to use and improved visualization of the veins, we found no evidence that it was superior to the standard method of intravenous cannulation in unselected pediatric patients under anesthesia.
Intrauterine growth retardation (IUGR) is associated with insulin resistance and lipid disorder. Tributyrin (TB), a pro-drug of butyrate, can attenuate dysfunctions in body metabolism. In this study, we investigated the effects of TB supplementation on insulin resistance and lipid metabolism in neonatal piglets with IUGR. Eight neonatal piglets with normal birth weight (NBW) and 16 neonatal piglets with IUGR were selected, weaned on the 7th day, and fed basic milk diets (NBW and IUGR groups) or basic milk diets supplemented with 0.1% tributyrin (IT group, IUGR piglets) until day 21 (n = 8). Relative parameters for lipid metabolism and mRNA expression were measured. Piglets with IUGR showed higher (P < 0.05) concentrations of insulin in the serum, higher (P < 0.05) HOMA-IR and total cholesterol, triglycerides (TG), non-esterified fatty acid (NEFA) in the liver, and lower (P < 0.05) enzyme activities (hepatic lipase [HL], lipoprotein lipase [LPL], total lipase [TL]) and concentration of glycogen in the liver than the NBW group. TB supplementation decreased (P < 0.05) the concentrations of insulin, HOMA-IR, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in the serum, and the concentrations of TG and NEFA in the liver, and increased (P < 0.05) enzyme activities (HL, LPL, and TL) and concentration of glycogen in the liver of the IT group. The mRNA expression for insulin signal transduction pathway and hepatic lipogenic pathway (including transcription factors and nuclear factors) was significantly (P < 0.05) affected in the liver by IUGR, which was efficiently (P < 0.05) attenuated by diets supplemented with TB. TB supplementation has therapeutic potential for attenuating insulin resistance and abnormal lipid metabolism in IUGR piglets by increasing enzyme activities and upregulating mRNA expression, leading to an early improvement in the metabolic efficiency of IUGR piglets.
Using a Langevin description of spinodal decomposition in fluids, we examine domain growth in the diffusive, viscous, and inertial regimes. In the framework of this model, numerical results corroborate earlier theoretical predictions based on scaling arguments and dimensional analysis. ͓S1063-651X͑96͒05505-5͔
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