Background:
The best site for splenic implant was not defined, mainly evaluating the
functionality of the implant.
Aim:
To evaluate the effects of autogenous splenic implantation on the
subcutaneous tissue in the survival of splenectomized rats.
Method:
Twenty-one randomly assigned rats were studied in three groups (n=7): group 1
- manipulation of the abdominal cavity and preservation of the spleen; group
2 - total splenectomy; group 3 - splenectomy and implant of the tissue
removed in the subcutaneous. The animals were followed for 90 days
postoperatively.
Results:
There was a higher mortality in groups 2 (p=0.0072) and 3 (p=0.0172) in
relation to group 1. There was no difference between groups 2 and 3
(p=0.9817).
Conclusion:
The splenic implant in the subcutaneous is ineffective in the survival of
rats submitted to splenectomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.