BackgroundThis study aimed to analyze the risk factors and treatment efficacy of neurobrucellosis.Material/MethodsA cross-sectional epidemiologic survey was carried out in 557 patients with brucellosis by specially trained neurologic clinicians. Sixty-six patients with neurobrucellosis were treated with doxycycline, rifampicin, and ceftriaxone sodium as standard medication and evaluated for efficacy on a regular basis.Results(1) Symptoms improved in most patients after 6 weeks of treatment, which demonstrated a favorable efficacy. (2) Cross-sectional epidemiologic survey suggested that sex, nationality, and regional distribution were not related to nervous system damage in patients with brucellosis (P>0.05), whereas age and duration of disease were related factors. Increased age as well as a prolonged duration of disease were risk factors for nervous system damage in patients with brucellosis (P<0.05).Conclusions(1) Doxycycline, rifampicin, and third-generation cephalosporins should be considered both standard and first-choice medications for neurobrucellosis. Treatment should last for at least 6 weeks. Standardized, sufficient, and combined medication is recommended for better efficacy and prognosis. (2) Age and duration of disease are risk factors for neurobrucellosis, whereas sex, nationality, and regional distribution are not. Older patients with a prolonged duration of disease are more likely to develop neurobrucellosis.
The paper focuses on the production process of clean steel combining with the production practice of Ansteel, and analyses the measures to improve the quality control of clean steel from two aspects: the selection of refractory materials and the tundish metallurgy. Practice has proved that the appropriate choice of refractory materials of refining equipment and reasonable use of tundish metallurgy, taking in the tundish dam, argon blowing, iron powder injection, adding the double slag and other measures which can reduce the metal inclusions below 1μm steel and will effectively control impurity elements in steel Σ (H, N, S, P, O) <80ppm.
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