Abt-Letterer-Siwe disease is a form of Langerhans cell histiocytosis and occurs in 2-10 cases per 1 million of the child population per year. The Russian and foreign literature provide descriptions of this disease in children of different ages. Family cases of this pathology are described in a small number. The chapter presents a rare clinical observation of the Abt-Letterer-Siwe disease in twin girls.
Perceived inadequate milk supply (PIMS) is a factor that hinders successful breastfeeding. The aim of our study was to determine the predictors of PIMS and to evaluate the effect of PIMS on the duration of lactation. More than 5000 mothers with children who had been breastfeeding for some time participated in our study. Analysis was performed using multivariate regression logistic and ROC statistical analyses. Eight predictors increasing the risk of PIMS were identified.
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