The Case of Langerhans Cell Histiocytosis (Abt-Letterer-Siwe Disease) in Twin Girls

Abstract

Abt-Letterer-Siwe disease is a form of Langerhans cell histiocytosis and occurs in 2-10 cases per 1 million of the child population per year. The Russian and foreign literature provide descriptions of this disease in children of different ages. Family cases of this pathology are described in a small number. The chapter presents a rare clinical observation of the Abt-Letterer-Siwe disease in twin girls.