Contemporary lab-chip devices require efficient, high-performance mixing capability. A series of artificial cilia with embedded magnetic particles was fabricated to achieve precise flow manipulation through magnetically driven control. These fabricated structures were actuated in a homogeneous magnetic field generated by a built-in magnetic coil system for various beating cycles inside a microchannel. Three representative trajectories, namely, circular motion, back-and-forth oscillation, and a figure-of-eight pattern, of artificial cilia were designed and generated to mimic the motion of actual cilia. Homogeneous mixing of two highly viscous (>25 centipoise) dyed solutions by using the figure-of-eight trajectory achieved a mixing efficiency of approximately 86%. The underlying relationship between ciliated structures and the induced flow fields was further elucidated by performing a hydrodynamic analysis with micro-particle image velocimetry. In addition, a numerical modeling method which used a fluid structure interaction module was applied to provide quantitative 3D illustrations of induced flow patterns, including vortical structures and vortex core locations. The results reveal that both the magnitude and distribution of induced vortices primarily affect the mixing performance of two viscous flow streams. By using magnetically controlled artificial cilia along with the presented analytical paradigms, a new active flow mixing strategy was suggested to efficiently transport/agitate flows for microfluidics and biomedical applications.
Driven by the advancement of the ''lab-chip'' concept, a new beating behavior of artificial cilia was identified to meet the demands on rapid and complete fluid mixing in miniaturized devices. This beating behavior is characterized by an in-plane asymmetric motion along a modified figure-of-eight trajectory. A typically symmetric figure-of-eight motion was also tested for comparison. Results showed that with this new beating behavior, the mixing efficiency for complete mixing is 1.34 times faster than that with the typical figure-of-eight motion. More importantly, the required beating area was only approximately two-thirds of that in the typical figure-of-eight motion, which is beneficial for more compact designs of various ''lab-chip'' applications. The unique planar asymmetric motion of the artificial cilia, which enhanced the magnitudes of the induced three-dimensional (3D) flow, was identified by micro-particle image velocimetry (lPIV) measurement and numerical modeling as a major contributor in enhancing microscale mixing efficiency. Quantitatively, 3D vortical flow structures induced by the artificial cilia were presented to elucidate the underlying interaction between the artificial cilia and the surrounding flow fields. With the presented quantification methods and mixing performance results, a new insight is provided by the hydrodynamic advantage of the presented micromixing concept on efficiently mixing highly viscous flow streams at microscale, to leverage the attributes of artificial cilia in the aspect of microscale flow manipulation.
Swordfish, Xiphias gladius (Linnaeus, 1758), is a commercially important species that is widely distributed throughout three oceans. This species inhabits oceanic waters with preferred environmental ranges and migrates vertically to the surface layer for feeding. However, the spatial distribution pattern and habitat preferences of swordfish have been rarely studied in the Pacific Ocean due to the wide geographic range of this species. This study examined the spatial distribution and preferred ranges of environmental variables for swordfish using two approaches, generalized additive models and habitat suitability index methods, with different spatio-temporal data resolution scales. Results indicated that sea surface temperature is the most important factor determining swordfish spatial distribution. Habitat spatial pattern and preferred environmental ranges, estimated using various modeling approaches, were robust relative to the spatio-temporal data resolution scales. The models were validated by examining the consistency between predictions and untrained actual observations, which all predicted a high relative density of swordfish in the tropical waters of the central Pacific Ocean, with no obvious seasonal movement. Results from this study, based on fishery and remote sensing data with wide spatial coverage, could benefit the conservation and management of fisheries for highly migratory species such as swordfish and tuna.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.