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Biomass-derived membrane used for uranium extraction of natural seawater from the East China Sea through the formation of metal–phenolic networks.

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A novel adsorbent, zirconium(IV)-impregnated collagen fiber, was prepared. Zr(IV) was uniformly dispersed in collagen fiber, mainly through chemical bonds, and was able to withstand the extraction of water. This adsorbent is effective for the removal of fluoride from aqueous solutions. The adsorption capacity was 2.29 mmol/g at pH = 5.5 when 5.00 mmol/L fluoride solution was adsorbed by use of 0.100 g of adsorbent, and the extent of removal was 97.4% when the adsorbent dose was 0.300 g. The adsorption isotherms were well fitted by the Langmuir equation, and the maximum adsorption capacities calculated by the Langmuir equation were close to those determined by experiment. The adsorption capacity increased with rising temperature. These facts imply that the mechanism of chemical adsorption might be involved in the adsorption process of fluoride on the absorbent and that fluorides are adsorbed in the form of monolayer coverage on the surface of the adsorbent. The adsorption kinetics of fluoride onto Zr(IV)-impregnated collagen fiber could be described by Lagergren's pseudo-first-order rate mode. The investigation on desorption indicated that this adsorbent is easily regenerated by use of dilute NaOH solution.

The targeted therapy of metastatic melanoma is an important yet challenging goal that has received only limited attention to date. Herein, green tea polyphenols, (–)‐epigallocatechin‐3‐gallate (EGCG), and lanthanide metal ions (Sm 3+ ) are used as building blocks to engineer self‐assembled Sm III ‐EGCG nanocomplexes with synergistically enhanced tumor inhibitory properties. These nanocomplexes have negligible systemic toxic effects on healthy cells but cause a significant reduction in the viability of melanoma cells by efficiently regulating their metabolic pathways. Moreover, the wound‐induced migration of melanoma cells can be efficiently inhibited by Sm III ‐EGCG, which is a key criterion for metastatic melanoma therapy. In a mouse melanoma tumor model, Sm III ‐EGCG is directly compared with a clinical anticancer drug, 5‐fluorouracil and shows remarkable tumor inhibition. Moreover, the targeted therapy of Sm III ‐EGCG is shown to prevent metastatic lung melanoma from spreading to main organs with no adverse side effects on the body weight or organs. These in vivo results demonstrate significant advantages of Sm III ‐EGCG over its clinical counterpart. The results suggest that these green tea‐based, self‐assembled nanocomplexes possess all of the key traits of a clinically promising candidate to address the challenges associated with the treatment of advanced stage metastatic melanoma.

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