Nanozyme is an artificial enzyme with high catalytic activity, low cost, and good biocompatibility, which has received ever-increasing attention in recent years. Various inorganic and organic nanoparticles have been found...

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As one of the most widely used drugs, acetaminophen, is the leading cause of acute liver injury. In addition, acetaminophen‐induced liver injury (AILI) has a strong relationship with the overproduced reactive oxygen species, which can be effectively eliminated by nanozymes. To address these challenges, mesoporous PdPt@MnO2 nanoprobes (PPM NPs) mimicking peroxide, catalase, and superoxide dismutase‐like properties are synthesized. They demonstrate nontoxicity, high colloidal stability, and exceptional reactive oxygen species (ROS)‐scavenging ability. By scavenging excessive ROS, decreasing inflammatory cytokines, and inhibiting the recruitment and activation of monocyte/macrophage cells and neutrophils, the pathology mechanism of PPM NPs in AILI is confirmed. Moreover, PPM NPs’ therapeutic effect and good biocompatibility may facilitate the clinical treatment of AILI.

The oxygen evolution reaction is the most kinetically hindered process in water electrolysis. Thus, oxygen evolution catalysts are required to improve the reaction kinetics. Precious metal catalysts are highly active, but the raw materials are scarce and costly. Thus, catalysts based on earth-abundant elements have drawn attention, and high performance, low-cost, and practial catalysts have been reported. Of the precious-metal-free commercial electrocatalysts, cobalt oxides are among the most important, and their catalytic properties can be improved by incorporating other elements. In this paper, we report that electrodeposited cobalt stannide (CoSn2) is a highly efficient oxygen evolution electrocatalyst, showing long-term electrochemical stability under alkaline conditions. Under optimal conditions, the catalyst operates at overpotentials of 250 and 300 mV at current densities of 1 and 10 mA cm−2, respectively, and has a Tafel slope of 64 mV dec−1. Furthermore, the prepared CoSn2 shows good electrochemical stability, and the overpotential for catalytic current densities of 1 and 10 mA cm−2 remained stable during electrolysis for 110 h. The results indicate that the as-prepared CoSn2 shows oxygen evolution reaction activity comparable to P- and Se-containing cobalt-based benchmark catalysts and suggest that electrodeposited CoSn2 is an attractive noble-metal-free catalyst for water oxidation.

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Background The treatment and management of patients suffering from hypophosphatemic rickets (HR) remain a major challenge for dental practitioners and affected patients. Objectives To report a case of HR presenting with specific dental findings and to review the dental manifestations and treatment of HR patients. Methods Case: A 32-year-old male presented with multiple dental abscesses and short stature. A thorough history was taken followed by clinical oral examination, and relevant radiological investigation was done. Literature research: In 2020, electronic literature searches were carried out in PubMed and complemented by a careful assessment of the reference lists of the identified relevant papers. Articles and reports fulfilled the inclusion criteria: indexed reviews, case series and case reports in English and restricted to human studies were considered. Results The intraoral examination revealed multiple dental abscesses and general periodontal disease; the radiographic examination showed poorly defined lamina dura, large pulp chambers and periapical lesions. Based on the contents of the 43 articles identified in the search, the current knowledge of dental manifestations, treatment and management of HR was summarized. Conclusions As HR is a multisystem disease, multidisciplinary care is needed. By summarizing current evidences, we proposed an evidence-based dental management and provided recommendations on diagnosis and treatment of the disease. It is of profound clinical significance to acquire knowledge of the dental manifestations and provide optimal treatment options for patients.

Ceria-zirconia mixed oxide holds many advantages to be used as the support for palladium-based automotive three-way catalysts (TWCs) with excellent thermal stability [1]. However, substantial fraction of Pd can be encapsulated by the ceria-zirconia mixed oxides after redox aging at high temperature [2,3]. Thermal degradation of auto catalysts may be related with the metal-support interaction. To understand more detail of this interaction, model catalyst systems were prepared by deposition of a monolayer Pd onto a (111) Ce x Zr 1-x. O 2 (CZO)/(111)ZrO 2 :Y (YSZ) substrate in ultra high vacuum (UHV). The samples were then calcined in air, reduced in (H 2 +CO)/N 2 , and finally reoxidized in O 2 /N 2 . Cross sectional samples were made for analytical transmission electron microscopy (ATEM) investigation after each step in one redox cycle. It was found that the morphology change of the Pd particle is dramatic.