In order to respond correctly to a free form factual question given a large collection of texts, one needs to understand the question to a level that allows determining some of the constraints the question imposes on a possible answer. These constraints may include a semantic classification of the sought after answer and may even suggest using different strategies when looking for and verifying a candidate answer. This paper presents a machine learning approach to question classification. We learn a hierarchical classifier that is guided by a layered semantic hierarchy of answer types, and eventually classifies questions into finegrained classes. We show accurate results on a large collection of free-form questions used in TREC 10.
Building step-scheme (S-scheme) heterojunctions is newly emerging to be an efficient means to get excellent photocatalysts for water pollution control. Herein, a 2D/0D S-scheme heterojunction of C3N5/Bi2WO6 is synthesized by...
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In this paper, we study an application of deep learning to the advanced LIGO and advanced Virgo coincident detection of gravitational waves (GWs) from compact binary star mergers. This deep learning method is an extension of the Deep Filtering method used by George and Huerta (2017) for multi-inputs of network detectors. Simulated coincident time series data sets in advanced LIGO and advanced Virgo detectors are analyzed for estimating source luminosity distance and sky location. As a classifier, our deep neural network (DNN) can effectively recognize the presence of GW signals when the optimal signal-to-noise ratio (SNR) of network detectors ≥ 9. As a predictor, it can also effectively estimate the corresponding source space parameters, including the luminosity distance D, right ascension α, and declination δ of the compact binary star mergers. When the SNR of the network detectors is greater than 8, their relative errors are all less than 23%. Our results demonstrate that Deep Filtering can process coincident GW time series inputs and perform effective classification and multiple space parameter estimation. Furthermore, we compare the results obtained from one, two, and three network detectors; these results reveal that a larger number of network detectors results in a better source location.
Interrupted-sampling repeater jamming (ISRJ) is a new kind of coherent jamming to the large time-bandwidth linear frequency modulation (LFM) signal. Many jamming modes, such as lifelike multiple false targets and dense false targets, can be made through setting up different parameters. According to the “storage-repeater-storage-repeater” characteristics of the ISRJ and the differences in the time-frequency-energy domain between the ISRJ signal and the target echo signal, one new method based on the energy function detection and band-pass filtering is proposed to suppress the ISRJ. The methods mainly consist of two parts: extracting the signal segments without ISRJ and constructing band-pass filtering function with low sidelobe. The simulation results show that the method is effective in the ISRJ with different parameters.
Delayed graft function (DGF) is one of the major obstacles for graft survival for kidney recipients. It is profound to reduce the incidence of DGF for maintaining long-term graft survival. However, the molecular regulation of DGF is still not adequately explained and the biomarkers for DGF are limited. Exosomes are cell-derived membrane vesicles, contents of which are stable and could be delivered into recipient cells to exert their biological functions. Consequently, exosome-derived proteomic and RNA signature profiles are often used to account for the molecular regulation of diseases or reflect the conditional state of their tissue as biomarkers. Few researches have been done to demonstrate the function of exosomes associated with DGF. In this study, high-throughput sequencing was used to explore the miRNA expression profiling of exosomes in the peripheral blood of kidney recipients with DGF. We identified 52 known and 5 conserved exosomal miRNAs specifically expressed in recipients with DGF. Three coexpressed miRNAs, hsa-miR-33a-5p_R-1, hsa-miR-98-5p, and hsa-miR-151a-5p, were observed to be significantly upregulated in kidney recipients with DGF. Moreover, hsa-miR-151a-5p was positively correlated with the first-week serum CR, BUN, and UA levels of the kidney recipients after transplantation. Furthermore, we also analyzed functions and signaling pathways of the three upregulated miRNAs target genes to uncover putative mechanism of how these exosomal miRNAs functioned in DGF. Overall, these findings identified biomarker candidates for DGF and provided new insights into the important role of the exosomal miRNAs regulation in DGF.
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