Amphiphilic di-cationic photosensitizers C12-MB could accumulate over bacterial cells with lower aggregation due to planar stack possibility inhibition, which could enhance anti-bacterial photodynamic efficiency.
Triple structural factors, including sophorose affinity to envelope, hydrophobic association with membrane and electrostatic attraction, have contributed to enhanced antibacterial photodynamic therapy of sophorolipid conjugated toluidine blue.
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