ABSTRACT. We investigated the treatment effect of non-invasive infiltration on early caries caused by different degrees of enamel demineralization. Forty specimens of early enamel caries were prepared and divided into low and high demineralization groups. After treatment with non-invasive infiltration, the specimens were placed under cariogenic conditions. Color measurements were determined using a spectrophotometer 4 times to obtain chromatism values (ΔE1-ΔE4), including before and after production of artificial caries, and after infiltration treatment and re-demineralization. The effects of color change on early caries using non-invasive infiltration were compared between the 2 demineralization groups. Color differences before the production of artificial caries and after infiltration treatment and redemineralization could not be distinguished by direct observation. Color differences after the production of artificial caries and after infiltration treatment and re-demineralization could be distinguished by direct observation. There were no significant differences in the 4 chromatism values (ΔE1-ΔE4) between the 2 groups. Non-invasive infiltration Non-invasive infiltration technique changes caries colorshowed an excellent ability to mask white spot lesions and maintained high color stability. Treatment of high and low demineralization of enamel had the same masking effect.