MCE detects focal lesions in the upper and lower stomach with comparable accuracy with conventional gastroscopy. MCE is preferred by almost all patients, compared with gastroscopy, and can be used to screen gastric diseases without sedation. Clinicaltrials.gov number: NCT02219529.

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In this paper, we present a novel dual-bandpass filter based on the substrate-integrated waveguide (SIW) and spoof surface plasmon-polariton (SSPP) hybrid structure. In this design, periodic subwavelength H-shaped units are etched on the top SIW surface to support SSPP mode. The dispersion and transmission characteristics of the proposed SIW-SSPP filter are analyzed. The dual-bandpass feature is observed for resonant tunneling of the H-shaped elements, and the passbands can be controlled easily by adjusting the filter parameters. Simulated and measured results demonstrate excellent transmission performance of the proposed filter.

This paper presents a novel method to extract the phase shift and phase distribution from two interferograms simultaneously. By employing Hilbert–Huang transform based prefiltering, the background intensities and modulation amplitudes of the two interferograms are suppressed and normalized respectively. With the addition and subtraction operation of the two prefiltered interferograms, two parametric equations are achieved which can be regarded as the complex harmonic motion of the Lissajous figure. The phase of the Lissajous figure can be directly demodulated by the ellipse fitting algorithm. Apart from the advantages of other well-known two-step phase demodulation algorithms, i.e., high accuracy and efficiency of the Gram-Schmidt orthonormalization (GS) method and the less stringent requirement concerning the fringe number in the extreme value of interference (EVI) method, proposed Lissajous figure and ellipse fitting (LEF) approach has another bonus related to its robustness to the fluctuations of the fringe patterns noise, background intensity and modulation amplitude. Simulations demonstrate the outstanding performance of the proposed method, and experiments further corroborate its effectiveness.

Background: Paroxysmal sympathetic hyperactivity (PSH) is one of the important reasons for the high mortality and morbidity of traumatic brain injury (TBI). We aim to explore the role of the neutrophil extracellular traps (NETs) in the pathogenesis of sympathetic hyperexcitability after TBI and the underlying mechanisms, providing evidence for clinical treatment.Methods: Enzyme-linked immunosorbent assay was used to assess the plasma metanephrine and normetanephrine levels which represented the variation of the sympathetic system after TBI with rat diffuse axonal injury (DAI) model. NETs in the paraventricular nucleus (PVN) and circulating blood were examined using immunofluorescence and flow cytometry. Neutrophils-microglia co-culture system was established to further explore the effect of NETs on PSH and its mechanisms.Results: After TBI, metanephrine and normetanephrine levels began to increase at 9 h and peaked at 72 h. After the injury, the level of NETs kept increasing at 24 and 72 h in the PVN. A positive correlation was found between the concentration of the PVN NETs and blood catecholamine. Flow cytometry of peripheral blood cells revealed that NETs level in the injury group was higher than that in the control group. Immunofluorescence results confirmed the presence of NETs in the PVN after TBI. The positive result of immunoprecipitation suggested a correlation effect between LL37 and P2 × 7. Peptidyl arginine deiminase-4 (PAD4) inhibitor could inhibit the expression levels of MST1, YAP, and IL-1β. The hippo/MST1 pathway inhibitor could inhibit the expression levels of YAP and IL-1β.Conclusion: NETs formation in the PVN might be associated with sympathetic hyperactivity after TBI, which might relate to the activation of microglia cells and increased secretion of IL-1β via the hippo/MST1 pathway.

Based on our previously reported annular subaperture reconstruction algorithm with Zernike annular polynomials and matrix method, we provide an experimental demonstration by testing a parabolic mirror with the complementary annular subaperture interferometric method. By comparing the results of annular subaperture method with that of the classical auto-collimation method, it is shown that the reconstruction results are in good agreement with the auto-collimation measurement. In addition, we discuss some limitations of characterizing annular subaperture measurement data with finite Zernike coefficients in our algorithm, and also show the possibility of characterizing higher spatial frequency information with adequate Zernike coefficients. It is believable that the reported method can be extended to test the surface shape of some large concave aspheric mirrors with acceptable accuracy.