for data acquisition and informatics support. We thank the following persons affiliated with the

The clinical presentation and outcome of nocardiosis depend on the patient's initial immune status and underlying pulmonary condition. Severe forms were all iatrogenic, occurring after treatments altering the immune system.

COVID-19-associated respiratory illness may lead to ARDS. 1 In intubated patients with severe ARDS, early, prolonged, and repeated sessions of prone positioning (PP) decrease mortality rates. 2,3 Awake PP is feasible, improves oxygenation in some patients, and may prevent respiratory worsening, [4][5][6] The main objective of the present study was to evaluate the effect of PP on the outcome of spontaneously breathing patients with COVID-19 with acute respiratory failure. MethodsWe designed an exposed/nonexposed bicentric retrospective matched cohort study to assess the effectiveness of PP for patients hospitalized outside ICU with COVID-19 whose condition required oxygen.

Background: The use of self-expandable metallic stents (SEMS) in benign airway disease was the object of a boxed warning from the United States Food and Drug Administration in 2005 due to the risk of stent-related complications and difficulties associated with their removal. Third-generation fully covered SEMS have been commercialized since this warning and theoretically should not present the same difficulties associated with removal as they cannot become embedded in the airway mucosa. Objectives: We aimed to examine the safety and efficacy of a specific third-generation SEMS, the Silmet stent. Methods: We reviewed the records of all patients treated for benign airway stenosis with third-generation Silmet SEMS from January 2011 to December 2015 at the North Hospital of Marseilles, France. Results: Forty SEMS were inserted in 30 patients over this period. Twenty (50.0%) stents were removed because of stent-related complications after a median of 77.0 ± 96.6 days (migration 32.5%, granulation tissue formation 7.5%, subjective intolerance 5.0%, mucus plugging 2.5%, laryngeal edema 2.5%). There were no cases of stent-related mortality. All complications were managed successfully endoscopically. Thirty-six stents (90.0%) were removed successfully after a median of 122.0 ± 113.2 days without any complications. The clinical success rate of stent treatment was 40.7%. Conclusion: Third-generation SEMS are a safe treatment option for complex benign airway stenosis, but complications requiring stent removal are frequent. Further studies are needed to compare the performance of third-generation SEMS and silicone stents in benign airway stenosis.