Summary ― A 61-d study involving 40 crossbred lambs evaluated the effect of various forms of tocopherol provided daily in equimolar amounts on total cholesterol, high-density lipoproteincholesterol and triglyceride concentrations in the serum of lambs. Thirty-five lambs were allotted to 7 treatment groups of 5 animals each, supplemented with 300 mg tocopherol either as: 1) DL -atocopheryl acetate; 2) D -a-tocopheryl acetate; 3) D- 0.05) for any serum measured component. The present data strongly suggest that short-term treatment (< 2 mo) with pharmacological oral doses of various forms of vitamin E did not influence serum lipid metabolism of lambs. The data also showed that the bioavailability of cc-tocopherol is dependent on the form administered. D -a-tocopherol acetate is a highly available form, the bioavailability of which is further increased when combined with o-a-tocopheryl polyethylene glycol succinate.
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