When Shigella dysenteriae 1 exotoxin was
administered to patas monkeys seven times, the number
of animals with neuron cell and basic myelin protein
autoantibodies increased. These antibodies were principally
IgG and IgM both in adolescent and adult animals. Inactivated
exotoxin did not have the same effect, nor the
injection of only three exotoxin doses.
Five groups of vervet monkeys (Cercopithecus aethiops) were fed regular
monkey chow, low protein (LP), low B-vitamin complex (LBV), LP-LBV, or low
protein - low calorie (LP-LC) diets, respectively. After eight weeks the animals were
infected with cholera vibrios. IgG, IgA and IgM increased in the sera of all animals after
the challenge but the avidity of the immunoglobulins was lower in vervets on LP diets.
Diarrhea and excretion of vibrios lasted longer in animals consuming less protein.
Lymphoid cell cultures from normal howler monkey (Alouatta caraya) lymph
nodes or peripheral blood were found to survive for over four months. Several-fold increase
in cell numbers occurred during the first two months of culture. The cells were predominantly
of T-cell origin. Herpes or C-type virus or viral genomes were not detected in
these lymphoid type cultures.
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