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(1) It is impossible to distinguish the lesions of melioidosis from those of glanders by means of inspection with the naked eye or even with the microscope.(2) The symptoms and course of the two diseases are similar. Melioidosis generally runs a more acute course.(3) The mallein test was applied in a case of chronic human melioidosis and gave a positive reaction. The mallein was obtained from Java.(4) The blood of this chronic case agglutinated the Muktesar and Java strains of B. mallei to full titre and the Minett strain to 10 per cent, of this amount. One of these strains (Muktesar) absorbed the agglutinins for the homologous bacillus.(5) There are very few horses in the Federated Malay States. Melioidosis is primarily a disease of rodents. All attempts to infect horses have been unsuccessful.(6) Melioidosis broke out spontaneously among the rabbits, guinea-pigs and rats at the Institute for Medical Research in 1913. The animals became infected through eating contaminated food.(7) Cases of infection in wild rats and in a domestic cat have occurred far away from this laboratory and independently of it.(8) Rabbits, guinea-pigs and rats have been infected experimentally, by feeding, by subcutaneous inoculation, by scarification and by the application of infective material to the nasal mucosa.(9) B. whitmori, whose growth in cultures occur in two forms, a commoner corrugated form and a mucoid form which gives origin to the corrugated type.(10) B. whitmori differs from B. mallei in the following particulars. It is actively motile. It forms a corrugated growth on glycerine agar, a white opaque growth on ordinary agar and a pellicle on the surface of broth. It grows more rapidly than B. mallei, and it liquefies gelatine in a few days.(11) B. whitmori resembles B. mallei in the following particulars. The morphology of the organisms is similar. Young cultures of the mucoid form are indistinguishable from B. mallei, by inspection. The growth of the mucoid form on potato is similar. The action on milk and carbohydrates differs in degree only. Both organisms produce Strauss's reaction in guinea-pigs.(12) Five strains of B. mallei were compared with fourteen strains of B. whitmori. The cultures of B. mallei comprised three from the National Collection at the Lister Institute, one from Muktesar and one from Java. The cultures of B. whitmori had been isolated, some from human cases of melioidosis and some from animals which had acquired the disease naturally.(13) The serological reactions of these organisms, namely agglutination, absorption and complement-fixation tests, showed that the cultures of B. whitmori were a homogeneous group, but the five strains of B. mallei were sharply divided into two sub-groups by their serological reactions. One sub-group includes the Muktesar and Java strains; the other comprises the three strains from the National Collection (Minett, Egypt and A.).(14) The first sub-group of B. mallei is very closely related to B. whitmori. The serological reactions of the strain from Muktesar are almost identical with those of B. whitmori.(15) The three strains of B. mallei from the National Collection, which form the second sub-group, are only distantly related to the Muktesar sub group and to B. whitmori.

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*Background: Over the course of recent years smartphone and tablet technology has evolved rapidly. Similarly, the sphere of healthcare is constantly developing and striving to embrace the newest forms of technology in order to optimise function. Many opportunities for mobile applications (i.e. 'apps') pertinent to the healthcare sector are now emerging. Objective: This study will consider whether registered pharmacists within the United Kingdom (UK) believe it appropriate to use mobile apps during the provision of healthcare within the community setting. Methods: Further to Liverpool John Moores University (LJMU) ethical approval, the 30 item questionnaire was distributed to UK registered pharmacists (n=600) practising within inner city Manchester, Liverpool and Newcastle. The questions were formatted as multiple choice, Likert scales or the open answer type. On questionnaire completion and return, data were analysed using simple frequencies, cross tabulations and nonparametric techniques in the Statistical Package for the Social Sciences (SPSS) (v18). Results: The majority of respondents (78.4% of 211 participants) confirmed that they were confident when using mobile apps on their technology platform. In general, mobile apps were perceived to be useful in facilitating patient consultations (55%) and supporting healthcare education (80%). The main barrier for mobile app use within the workplace was company policy, deemed significant in the case of regional / national chain pharmacies (p<0.001). Pharmacists alluded to the fact that whilst mobile apps demonstrate potential in modern day practise, they will have a greater impact in the future (p<0.001). Conclusion:The data indicate that although pharmacists are supportive of mobile apps in healthcare, a number of factors (i.e. risk, company policy and lack of regulation) may preclude their use in modern day pharmacy practise. Clearly, limitations of the technology must be addressed in order to maximise uptake within healthcare systems. Pharmacists suggest that as the younger generation ages, mobile apps will become a more accepted method by which to manage healthcare in the wider population.

MBoRTSH 431 distributions of symptoms at the first examination were very similar for the two groups.The results for the patients who reported on each of the three days are shown in Table II. On each day the proportion recovering was slightly smaller in the treated than in the control series, but none of the differences is statistically significant. The experience of the patients with incomplete records is shown in Table III. In this group the controls also showed a statistically insignificant advantage over the treated. No direct or indirect questions were asked concerning possible side-effects. The number of patients who had conditions which they attributed to the treatment was too small for detailed analysis, for only 14 in the treated group and 13 in the control group complained that the tablets had any adverse effects. Most of the symptoms described could in fact have been symptoms of the cold. ConclusionA large-scale trial of antistin failed to show that this drug had any effect on the course of the common cold.We are greatly indebted to the managements and medical staffs of the centres where the trials were carried out, and we should like to thank the following people in particular for their co-operation and assistance: