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The osteogenic predifferentiated BMSC sheet can act as a scaffold-free TEP to facilitate bone regeneration. Hence, our study provides a promising strategy for enhancing bone regeneration in clinical settings.

Effective methods to shorten the treatment period of distraction osteogenesis (DO) are needed. To investigate whether injections of osteogenic bone marrow stromal cell (BMSC) sheet fragments could be used to facilitate new bone formation during DO, 30 rabbits underwent bilateral mandibular osteotomy and their mandibles were lengthened at a rate of 0.75 mm/12 h for 6 days after a 5-day latency period. There were three treatment groups (n ¼ 10 for each group): Serum-free medium, dissociated BMSCs, and BMSC sheet fragments. A local injection was conducted with a needle directly into the distracted areas immediately after distraction. Rabbits were sacrificed for examination at 3 and 6 weeks after injection. Gross examination, radiographic evaluation, and micro-CT scanning indicated a significant increase in bony union in the BMSC sheet fragment group, compared with the medium group and the dissociated cell group. The histomorphometric analysis showed more intensive bone formation in the sheet fragment group than the other two groups at each time point. Additionally, the peak load was significantly higher in the fragment group than those in the others. The results show that injection of BMSC sheet fragments promotes bone formation in DO and indicate a promising approach to shorten the treatment period of osteodistraction. #

Using the first-principles calculations, the electronic structure, chemical bonding, mechanical, thermodynamics and superconductor properties of NbRuB are investigated. The optimized lattice parameters were in good agreement with the experimental data. The analysis of the density of states and chemical bonding implies that the metallic behavior of NbRuB originates from the Ru and Nb, and the bonding behaviors are a mixture of covalent-ionic bonds. The bulk modulus, shear modulus, Young’s modulus, Poisson’s ratio and hardness of NbRuB were calculated. The results reveal that the NbRuB is ductility and the Vickers hardness is 15.06 GPa. Moreover, the 3D dependences of reciprocals of Young’s modulus is also calculated and discussed, showing strong anisotropic character for NbRuB. Finally, the Debye temperature and superconducting transition temperature are obtained.

Creation of sustainable, cost-effective, and scalable absorbents with ideal absorption properties is a worldwide challenge because many high-performance absorbents are still restricted in laboratory scope due to several critical defects (like complex and eco-unfriendly synthesis process, high cost, and difficulty in large-scale production). Herein, a facile and scalable top-to-bottom design is proposed to create a kind of novel anisotropic carbon aerogels with low tortuosity of stacked laminated structure, derived from the hierarchical cellular channels of balsa wood. By virtue of this unique structure and favorable oleophilicity, fast passive capillary absorption with low flow resistance is achieved (as demonstrated by the theoretical modeling). As a result, the anisotropic carbon aerogels have quite sensitive selectivity to separate organic pollutants from water, broad-spectrum and high absorption capacity for different organic liquids (13 277–31 597 mg g–1), and superior recyclability (98.7% absorption capacity retention after five cycles). Combining these outstanding performances with a cheap preparation strategy as well as good environmental friendliness, this work provides a kind of potential scalable materials for efficient reusable absorption and separation of organic leakages.

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Traditional noble metal-based catalysts for glucose sensing usually suffer from easy deactivation by halides and weak sensing properties. To unravel these limits, herein, a novel nature-inspired design concept (mimicking a "rock-soil-grass" geotexture system) is purposed to build a free-standing hierarchical micro-nano architecture. Thanks to the design (rigid and conductive Ni foam) ("rock", underlayer, rough and highly disordered graphene nanosheets (GNSs) ("soil", middle-layer), and strong catalytic activity of multiscale grass-like Co 3 O 4 ("grass", top-layer), the bionic structure achieves ultra-high sensitivity, a low limit of detection (120 × 10 −9 m), an extremely short response time, broad linear ranges (two stages: 1-10 000 and 10 000-30 040 µm), good anti-Cl − -poisoning and anti-interference properties, and long-term stability. Besides the structural design, the "gotong-royong" effects (the strong interface coupling and charge transfer between GNSs and Co 3 O 4 and energetically favorable glucose adsorption on Co 3 O 4 ) also contribute to the high sensing properties, as verified by kinetic studies and density functional theory simulation. To determine human blood glucose levels, the self-made glucometer with the self-developed software demonstrates an ultra-high recovery rate (99.0-100.9%), validating the potential for highperformance blood-glucose sensing.