Middle-wave band infrared imagers and long -wave band infrared imagers have their own advantage and disadvantage under different scenario. Nowadays, the infrared imaging detection system has been developed to the third generation: dual/multi band infrared imager. For a dual/multi band infrared imager, image fusion is a significant research topic. The core of dual band infrared image fusion is to integrate corresponding information from different band infrared imager into a new image. We proposed a new image fusion technology for middle-band infrared image and long-wave infrared image. This technology firstly extracts elementary image semantic, and fuses middle-band infrared image and long-wave infrared image in terms of their elementary image semantic, and then colours the new fusion image in terms of the response characteristics of the scenario in different bands. Finally, the experiment shows the effectiveness of our fusion technology.
Glioma is the most prevalent type of primary brain tumor, and glioblastoma multiforme (GBM) is the highest and most deadly type of primary central nervous system (CNS) tumor, affecting a significant number of patients each year, with a median overall survival of approximately 14.6 months after diagnosis. Despite intensive treatment, nearly all GBM patients experience recurrence, with a 5-year survival rate of about 5%. The protective BBB and high tumor heterogeneity prevent the effective delivery of drugs, resulting in the treatment failure of various drugs. The emergence of nanometer-scale diagnosis and treatment methods has provided new promising approaches to overcome these difficulties. Thus, our review focuses on the development of BBB-crossing nanomedicine-enhanced chemotherapy and combined therapy applications for glioma. Meanwhile, we also reviewed the strategies to overcome the blood–brain barrier. Additionally, we discuss recent achievements in the area of brain tumor treatment with nanomedicine and the rational design approach, which will offer recommendations for anti-GBM nanomedicine development.
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