BindingDB () is a publicly accessible database currently containing ∼20 000 experimentally determined binding affinities of protein–ligand complexes, for 110 protein targets including isoforms and mutational variants, and ∼11 000 small molecule ligands. The data are extracted from the scientific literature, data collection focusing on proteins that are drug-targets or candidate drug-targets and for which structural data are present in the Protein Data Bank. The BindingDB website supports a range of query types, including searches by chemical structure, substructure and similarity; protein sequence; ligand and protein names; affinity ranges and molecular weight. Data sets generated by BindingDB queries can be downloaded in the form of annotated SDfiles for further analysis, or used as the basis for virtual screening of a compound database uploaded by the user. The data in BindingDB are linked both to structural data in the PDB via PDB IDs and chemical and sequence searches, and to the literature in PubMed via PubMed IDs.

Localized surface plasmon resonances (LSPRs) are achieved in heavily doped semiconductor nanoparticles (NPs) with appreciable free carrier concentrations. In this paper, we present the photonic, electric, and photoelectric properties of plasmonic Cu2-xS NPs/films and the utilization of LSPRs generated from semiconductor NPs as near-infrared antennas to enhance the upconversion luminescence (UCL) of NaYF4:Yb(3+),Er(3+) NPs. Our results suggest that the LSPRs in Cu2-xS NPs originate from ligand-confined carriers and that a heat treatment resulted in the decomposition of ligands and oxidation of Cu2-xS NPs; these effects led to a decrease of the Cu(2+)/Cu(+) ratio, which in turn resulted in the broadening, decrease in intensity, and red-shift of the LSPRs. In the presence of a MoO3 spacer, the UCL intensity of NaYF4:Yb(3+),Er(3+) NPs was substantially improved and exhibited extraordinary power-dependent behavior because of the energy band structure of the Cu2-xS semiconductor. These findings provide insights into the nature of LSPR in semiconductors and their interaction with nearby emitters and highlight the possible application of LSPR in photonic and photoelectric devices.

In the above article, the dataset code number PASS00296 for the mass spectrometry data of the SFB-YTHDC1 tandem-affinity purification on peptideatlas.org was incorrect. The authors regret this error. It has now been replaced with the correct dataset code number, PASS00835, in the online version.

The performance of perovskite solar cells (PSCs) strongly depends on the electron transport layer (ETL), perovskite absorber, hole transport layer (HTL), and their interfaces. Herein, the first approach to utilize ultrathin 2D titanium‐carbide MXenes (Ti3C2Tx quantum dots, TQD) by engineering the perovskite/TiO2 ETL interface and perovskite absorber and introducing Cu1.8S nanocrystals to perfect the Spiro‐OMeTAD HTL is represented. A significant hysteresis‐free power conversion efficiency improvement from 18.31% to 21.64% of PSCs is achieved after modifications with the enhanced short‐circuit current density, open‐circuit voltages, and fill factor. Various advanced characterizations, including femtosecond transient absorption spectroscopy, electrochemical impedance spectroscopy, and ultraviolet photoelectron spectroscopy, elucidate that the TQD/Cu1.8S significantly contribute to the improved crystalline quality of the perovskite film with its large grain size and improved electron/holes extraction efficiencies at perovskite/ETL and perovskite/HTL interfaces. Furthermore, the long‐time ambient and light stability of PSCs are largely boosted through the TQD and/or Cu1.8S nanocrystals doping, originating from the better crystallization of perovskite, suppressing the film aggregation and crystallization of HTL, and inhibiting the ultraviolet‐induced photocatalysis of the ETL. The findings highlight the TQD and Cu1.8S can act as a superfast electrons and holes tunnel for the optoelectronic devices.

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Luminescent upconversion is a promising way to harvest near-infrared (NIR) sunlight and transforms it into visible light that can be directly absorbed by active materials of solar cells and improve their power conversion efficiency (PCE). However, it is still a great challenge to effectively improve the PCE of solar cells with the assistance of upconversion. In this work, we demonstrate the application of the transparent LiYF4:Yb(3+), Er(3+) single crystal as an independent luminescent upconverter to improve the PCE of perovskite solar cells. The LiYF4:Yb(3+), Er(3+) single crystal is prepared by an improved Bridgman method, and its internal quantum efficiency approached to 5.72% under 6.2 W cm(-2) 980 nm excitation. The power-dependent upconversion luminescence indicated that under the excitation of simulated sunlight the (4)F(9/2)-(4)I(15/2) red emission originally results from the cooperation of a 1540 nm photon and a 980 nm photon. Furthermore, when the single crystal is placed in front of the perovskite solar cells, the PCE is enhanced by 7.9% under the irradiation of simulated sunlight by 7-8 solar constants. This work implies the upconverter not only can serve as proof of principle for improving PCE of solar cells but also is helpful to practical application.

The surface plasmon (SP) modulation is a promised way to highly improve the strength of upconversion luminescence (UCL) and expand its applications. In this work, the "islands" Au-Ag alloy fi lm is prepared by an organic removal template method and explored to improve the UCL of NaYF 4 : Yb3+, Tm 3+ /Er 3+ . After the optimization of Au-Ag molar ratio (Au 1.25 -Ag 0.625 ) and the size of NaYF 4 nanoparticles (NPs, ≈7 nm), an optimum enhancement as high as 180 folds is obtained (by refl ection measurement) for the overall UCL intensity of Tm 3+ . Systematic studies indicate that the UCL enhancement factor (EF) increases with the increased size of metal NPs and the increase of diffuse refl ection, with the decreased size of NaYF 4 NPs, with the decreased power density of excitation light and with improving order of multiphoton populating. The total decay rate varies only ranging of about 20% while EF changes signifi cantly. All the facts above indicate that the UCL enhancement mainly originates from coupling of SP with the excitation electromagnetic fi eld. Furthermore, the fi ngerprint identification based on SP-enhanced UCL is realized in the metal/UC system, which provides a novel insight for the application of the metal/UC device.

In this paper, a new anti-disturbance controller is presented for a class of non-linear systems with multiple disturbances. The first part of the disturbance is described by an exogenous model and the second part represents an uncertain variable bounded by a given function. A new non-linear disturbance observer is designed to estimate the composite disturbances. Then, a hierarchical control strategy consisting of disturbance-observer-based control and a robust adaptive controller is presented to achieve the anti-disturbance performance. A stability analysis for both the error estimation systems and the composite closed-loop system is provided. Finally, the approach is applied to a missile control system to show the efficiency of the approach.