It is found that Keggin-type of polyoxometalates nanocubes could be formed in aqueous medium under the adjustment of dimethylformamide (DMF), and could be changed from solid nanocubes to hollow ones with increasing temperature. Further investigations show that this Keggin-type of polyoxometalates nanocubes can specifically interact with prion protein, and the light scattering signals are enhanced in proportion to the content of prion in the range of 3.36-840 ng·mL -1 .
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.