Objective
To explore the risk factors including the difference between mean gestational sac diameter and crown-rump length for missed abortion.
Methods
Hospitalized patients with missed abortion and patients with continuing pregnancy to the second trimester from Chengdu Women's and Children's Central Hospital from June 2018 to June 2021 were retrospectively analyzed. The best cut-off value for age and difference between mean gestational sac diameter and crown-rump length (mGSD-CRL) were obtained by x-tile software. Univariate and multivariate logistic regression analysis were adopted to identify the possible risk factors for missed abortion.
Results
Age, gravidity, parity, history of cesarean section, history of recurrent abortion (≥ 3 spontaneous abortions), history of ectopic pregnancy and overweight or obesity (BMI > 24 kg/m2) were related to missed abortion in univariate analysis. However, only age (≥ 30 vs < 30 years: OR = 1.683, 95%CI = 1.017–2.785, P = 0.043, power = 54.4%), BMI (> 24 vs ≤ 24 kg/m2: OR = 2.073, 95%CI = 1.056–4.068, P = 0.034, power = 81.3%) and mGSD-CRL (> 20.0vs ≤ 11.7 mm: OR = 2.960, 95% CI = 1.397–6.273, P = 0.005, power = 98.9%; 11.7 < mGSD-CRL ≤ 20.0vs > 20.0 mm: OR = 0.341, 95%CI = 0.172–0.676, P = 0.002, power = 84.8%) were identified as independent risk factors for missed abortion in multivariate analysis.
Conclusion
Patients with age ≥ 30 years, BMI > 24 kg/m2 or mGSD-CRL > 20 mm had increasing risk for missed abortion, who should be more closely monitored and facilitated with necessary interventions at first trimester or even before conception to reduce the occurrence of missed abortion to have better clinical outcomes.
In the digital era of rapid information growth, students’ value positions are easily attacked by all kinds of bad information, leading to the wrong way. Scientific and reasonable design of computer public basic course ideological and political teaching cases can not only improve students’ participation in class, but also help guide students’ values and establish correct value orientation. This paper explores an applied approach in education that embeds ideological and political perspectives into various chapters of the course, achieving good practical results and improving teaching effectiveness in many ways.
Despite over 90% of China’s coastal bays have an area less than 500 km2, the geochemical effects of SGD on those ecosystems are ambiguous. Based on mapping and time-series observations of Ra isotopes and nutrients, a case study of small bays (<500 km2), we revealed that submarine groundwater discharge (SGD) predominately regulated the distribution of nutrients and fueled algal growth in Dongshan Bay, China. On the bay-wide scale, the SGD rate was estimated to be 0.048 ± 0.022 m day−1 and contributed over 95% of the nutrients. At the time-series site where the bay-wide highest Ra activities in the bottom water marked an SGD hotspot with an average rate an order of magnitude greater, the maximum chlorophyll concentration co-occurred, suggesting that SGD may support the algal bloom. The ever-most significant positive correlations between 228Ra and nutrients throughout the water column (P< 0.01, R2 > 0.90 except for soluble reactive phosphorus in the surface) suggested the predominance of SGD in controlling nutrient distribution in the bay. Extrapolated to a national scale, the SGD-carried dissolved inorganic nitrogen flux in small bays was twice as much as those in large bays (>2,000 km2). Thus, the SGD-carried nutrients in small bays merit immediate attention in environmental monitoring and management.
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