Optical resonators are sensors well known for their high sensitivity and fast response time. These sensors have a wide range of applications, including in the biomedical fields, and cancer detection is one such promising application. Sensor diagnosis currently has many limitations, such as being expensive, highly invasive, and time-consuming. New developments are welcomed to overcome these limitations. Optical resonators have high sensitivity, which enable medical testing to detect disease in the early stage. Herein, we describe the principle of whispering-gallery mode and ring optical resonators. We also add to the knowledge of cancer biomarker diagnosis, where we discuss the application of optical resonators for specific biomarkers. Lastly, we discuss advancements in optical resonators for detecting cancer in terms of their ability to detect small amounts of cancer biomarkers.
Microscope add-on toolkits for smartphone and tablet have become more widely available in the market. Although, these are sufficient to meet the demand and requirements of standard users, e.g. educational usage, these devices, in fact, do not meet the medical and biological requirements where fluorescence imaging plays a crucial role. In this paper, we introduce our innovative design in compact fluorescence microscope for smartphone and tablet. The device enables users to take fluorescent images at several excitation wavelengths using compact sources and filters.
Refractive index and Abbe number are major physical properties of optical materials including glasses and transparent polymers. Refractive index is, in fact, not a constant number and is varied as a function of optical wavelength. The full refractive index spectrum can be obtained using a spectrometer. However, for optical component designers, three refractive indices at the wavelengths of 486.1 nm, 589.3 nm and 656.3 nm are usually sufficient for most of the design tasks, since the rest of the spectrum can be predicted by mathematical models and interpolation. In this paper, we propose a simple optical instrumental setup that determines the refractive indices at three wavelengths and the Abbe number of solid and liquid materials.
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