The prevalence of degenerative diseases increases with age. Furthermore, various factors tend to trigger cells injury, thereby, causing inflammation. This study, therefore, aims to examine the anti-inflammatory mechanisms of steeping date seeds in middle age women. This is a quasi-experimental design with a pre- and post-test approach used to evaluate the anti-inflammatory effect of 2.5 g of steeped of date palm seed, consumed by 30 healthy middle-aged women per day (in 250 mL water) for 14 days. The final numbers (22 subjects) of recruited women were included in the statistical analysis. Their level of IL-1β, TGF-β, IL-6, TNF-α, IL-12, COX-1, COX-2, and PGE2 were determined using ELISA. The results showed that the expression of IL-1β, TGF-β, COX-1, and COX-2 in women significantly decreased after consuming date palm seed. Steeped of date seed acts as an anti-inflammatory by downregulating the expression of key proinflammatory mediators.
Ageratum conyzoides Linn. is known as billy goat weed, including the family Asteraceae. This plant has been used empirically as a medicine for diarrhea, scratches, antinflammatory, snakebite, insecticide and nemasiticide. This study aims to identify plants based on pharmacognitive profiles including macroscopy, microscopy and non-parametric characters from plant parts of ageratum conyzoides to determine the standardization of herbs. The results showed that the leaves were ovoid, pale green, soft hairy and purple, bluish or white flowers flowers. Microscopic observations of cross section of stem and leaf showed the presence of parenchyma cells, collenchyma cells and multicellular non-glandular trichomes, upper and lower epidermal cells, stomata in the upper and lower epidermis of the leaf. The highest value of water content was in the radix. The highest value of ash content was in the stem. The highest value of acid soluble ash content was in the radix. The highest value of water-soluble extract was in the folium. The highest value of ethanol-soluble extract was in the flower. The results of this study can be used as authentication of plant parts and a basis for the analysis of the standard pharmacopoeia A. conyzoides.
Introduction: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) better known as Covid-19 is a new type of coronavirus that transmitted to humans. This virus is contagious quickly and has spread to almost all countries, including Indonesia, in just a few months. Public awareness and behavior are needed to prevent and control COVID-19.
Objective: This activity aimed to increase public knowledge and attitudes to actively participate in preventing and controlling the transmission of Covid 19.
Method: The implementation of this activity begins with the process of evaluating the level of knowledge and attitudes of PKK cadres regarding the prevention and control of Covid-19 by conducting a pre-test using a questionnaire. Then, the team provided education about the prevention and control of Covid-19 by using appropriate media. This activity was carried out using the transfer & sharing method of knowledge by using aids of audiovisual media and leaflets. Besides being open for discussion sessions, questions, and answers related to Covid-19.
Result: The results showed an increase in respondents' knowledge before and after education by as much as 47%, while the attitudes of respondents showed an increase before and after education by as much as 47%.
Conclusion: We concluded that providing education related to Covid 19 could increase people's knowledge and attitudes.
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