We determined the effects of helium-neon (He-Ne) laser irradiation on wound healing dynamics in mice treated with steroidal and nonsteroidal anti-inflammatory agents. Male albino mice, 28-32 g, were randomized into 6 groups of 6 animals each: control (C), He-Ne laser (L), dexamethasone (D), D + L, celecoxib (X), and X + L. D and X were injected im at doses of 5 and 22 mg/kg, respectively, 24 h before the experiment. A 1-cm long surgical wound was made with a scalpel on the abdomens of the mice. Animals from groups L, D + L and X + L were exposed to 4 J (cm 2 ) -1 day -1 of He-Ne laser for 12 s and were sacrificed on days 1, 2, or 3 after the procedure, when skin samples were taken for histological examination. A significant increase of collagen synthesis was observed in group L compared with C (168 ± 20 vs 63 ± 8 mm 2 ). The basal cellularity values on day 1 were: C = 763 ± 47, L = 1116 ± 85, D = 376 ± 24, D + L = 698 ± 31, X = 453 ± 29, X + L = 639 ± 32 U/mm 2 . These data show that application of L increases while D and X decrease the inflammatory cellularity compared with C. They also show that L restores the diminished cellularity induced by the anti-inflammatory drugs. We suggest that He-Ne laser promotes collagen formation and restores the baseline cellularity after pharmacological inhibition, indicating new perspectives for laser therapy aiming to increase the healing process when anti-inflammatory drugs are used.

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INTRODUÇÃO: O alongamento passivo ou estático (EAL) é frequentemente utilizado em programas de reabilitação e na área desportiva; porém, as alterações morfofuncionais ocorridas ainda não estão bem claras, principalmente após imobilização prolongada. OBJETIVOS: Examinar as alterações morfofuncionais musculares produzidas em resposta a três semanas de exercícios de EAL em um modelo animal de imobilização prolongada de membro posterior (MP) em posição encurtada. MÉTODOS: Foram utilizados 32 ratos Wistar divididos em quatro grupos (n = 8, em cada): A - grupo controle (CONT), B - grupo imobilizado por 21 dias (IMOB), C - grupo remobilizado por 21 dias (LIVRE), D - grupo alongados por 21 dias (ALONG). Foram comparadas as variações morfofuncionais entre grupos experimentais. As variáveis foram: peso corporal e muscular, comprimento muscular e ósseo, número de miofibrilas e quantidade de colágeno, determinadas através de histomorfometria muscular por contraste de cor. RESULTADOS: A IMOB do bíceps femoral em posição encurtada produziu uma importante hipotrofia com hiperplasia muscular compensatória, além do aumento (p < 0,05) na deposição de colágeno no perimísio e intramuscular de ratos. A remobilização livre ou o alongamento passivo reduziram significativamente (p < 0,05) estas alterações morfofuncionais observados no grupo IMOB. CONCLUSÃO: Através desses resultados, pode-se concluir que tanto o EAL quanto a remobilização livre promovem a restauração das alterações morfofuncionais no bíceps femoral esquerdo induzida pela imobilização prolongada, embora somente o EAL foi capaz de reduzir a relação entre colágeno/músculo.

Objective: To investigate gender differences in neuronal sensory threshold (NS) for transcutaneous electrical nerve stimulation (TENS) among young adults, and the probable effects of thermotherapy. Methods: 30 young healthy students (15 men and 15 women) with 22±2 years old were divided by gender. TENS was applied in both right and left knees of subjects with a frequency of 20 Hz and pulse duration of 230µs. The amplitude RI WKH HOHFWULF FXUUHQW P ZDV JUDGXDOO\ LQFUHDVHG WR UHFRUG the perception threshold (ST) and tolerance threshold (TT), before/after thermotherapy. The warm R-knee was performed by LQIUDUHG OLJKW : § FP SHUSHQGLFXODU DQG FRROLQJ / NQHH with icepack, both carried out for 15 minutes. The tissue temperature was recorded by digital thermometry. The data were analyzed and differences established at p<0.05. Results: The WLVVXH WHPSHUDWXUH DIWHU KHDW WUHDWPHQWV ZDV GLIIHUHQW S between genders. The basal ST for TENS was not different between genders, however, thermotherapy raised the NS in both PHQ DQG ZRPHQ $W WKH EDVHOLQH 77 ZDV ORZHU S LQ ZRPHQ KRZHYHU DIWHU WKHUPRWKHUDS\ LW LQFUHDVHG S LQ both sexes. Conclusion: Neuronal sensory threshold for TENS is gender-thermo-dependent in healthy young adults.

Low-intensity ultrasound therapy (LIUST) has been described as a plausible treatment for chronic rhinosinusitis (CRS). Aims: To evaluate the short-term effects of continuous 1MHz LIUST on nasal obstruction in subjects with CRS. Material and Method: A cohort placebo-controlled study comprising 26 CRS adults (10 men, 16 women), sequentially allocated into two groups: control-placebo (CP, n= 12) and treated with LIUST (US, n= 14). The treatment consisted of: ISATA = continuous 1MHz, 1W.cm-2 for four minutes in the maxillary sinuses and nasal septum. The equipment was switched off in the CP group. The degree of obstruction was assessed by the total volume of secretion expelled (VSEx) after nasal instillation of 5 mL saline solution (NaCl-0.9%) followed by nasal lavage. The volume of expired air (VEA) was assessed with a Glatzel mirror. Results: The data showed an increase (p<0.01) in VSEx and VEA after ultrasound therapy, suggesting a 64% improvement of nasal obstruction compared with the CP group. Conclusions: Continuous LIUST reduced nasal obstruction and congestionç it may be used effectively in the respiratory therapy of CRS patients.

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The low level of physical activity and poor nutritional quality are related to metabolic alterations related to chronic diseases. Objective: To evaluate the level of physical activity and eating habits of university professors from a private educational institution, RJ, Brazil. Methods: cross-sectional study conducted in university professors at the Anhanguera University Center of Niterói, RJ. Data collected online (Microsoft forms): weight and height for nutritional status (low weight, normal weight , overweight and obesity and "excessive weight or no excessive weight "), international physical activity questionnaire IPAQ and "How is your diet?", a national questionnaire. Classification of physical activity level: low, moderate or high and classification of diet: poor, regular and excellent. Statistical analysis: SPSS, v.25. Results: 101 professors (female 51.4%), with means: 45.4 years, weight 79.2 kg, body mass index 27.4 kg/m2; 1% (n=1), 28.7% (n=29), 40.6% (n=41), 29.7% (n=30) were low weight, normal weight, overweight and obesity, respectively. Overweight in 70.3% of the sample (83.7% male). Poor, regular and excellent eating habits, 19.8% (n=20), 25.7% (n=26), 54.5 (n=55), with no significant difference by sex (p=0.31) and nutritional status (p=0.58). Low level of physical activity 31.7% (n=32), moderate level 34.7% (n=35), and high level 33.7% (n=34), more prevalent in men (p=0.048). Conclusion: High prevalence of overweight, approximately half of the sample with inadequate eating habits and one third with low level of physical activity. Professor's awareness about regular physical exercise and eating habits in health promotion is necessary, including institutional programs for this purpose. Keywords: Exercise. Feeding Behavior. Quality of Life. Resumo O baixo nível de atividade física e a má qualidade nutricional relacionam-se à alterações metabólicas preditoras de doenças crônicas. Objetivou-se avaliar o nível de atividade física e os hábitos alimentares de docentes universitários de uma instituição de ensino privada, RJ, Brasil. Estudo transversal em docentes universitários do Centro universitário Anhanguera de Niterói, RJ. Dados coletados online (Microsoft forms): pessoais, peso e estatura para estado nutricional (baixo peso, eutrofia, sobrepeso e obesidade e “sem e com excesso de peso”), questionário internacional de atividade física IPAQ e questionário do Ministério da Saúde “Como está sua alimentação?”. Classificação do nível de atividade física: baixo, moderado ou elevado e da alimentação: ruim, regular e excelente. Análise estatística: SPSS, v.25. Foram avaliados 101 docentes (feminino 51,4%), com médias: 45,4 anos, peso 79,2 kg, índice de massa corporal 27,4 kg/m2; 1% (n=1), 28,7% (n=29), 40,6% (n=41), 29,7% (n=30) apresentaram baixo peso, eutrofia, sobrepeso e obesidade, respectivamente. Excesso de peso em 70,3% da amostra (83,7% sexo masculino). Hábitos alimentares ruim, regular e excelente, 19,8% (n=20), 25,7% (n=26), 54,5 (n=55), sem diferença significativa por sexo (p=0,31) e estado nutricional (p=0,58). Identificou-se em 31,7% (n=32) nível de atividade física baixo, em 34,7% (n=35), moderado e em 33,7% (n=34), elevado, superior nos homens (p=0,048). O estudo apontou elevada prevalência de excesso de peso, inadequação nos hábitos alimentares e um terço com nível baixo de atividade física. Faz-se necessária a conscientização dos docentes acerca do exercício físico regular e dos hábitos alimentares na promoção da saúde, incluindo programas institucionais com este fim. Palavras-chave: Exercício Físico. Comportamento Alimentar. Qualidade de Vida.