The methanol, ethyl acetate and petroleum ether crude extracts of mangosteen pericarp and αmangostin were evaluated for the antioxidant capacity and tyrosinase inhibition properties. The ferric reducing antioxidant power (FRAP) assay was used to investigate their antioxidant capacity. Tyrosinase inhibition effect was evaluated using mushroom tyrosinase inhibition assay. Methanol extract has higher antioxidant reducing capacity (m= 1.621), compared to the rest of the extracts. Meanwhile, ethyl acetate extract and αmangostin showed potent tyrosinase inhibition activities as compared to Kojic acid, a well-known tyrosinase inhibitor. It is observed that tyrosinase inhibition effect is antioxidant independent as ethyl acetate extract possessed low antioxidant capacity. This study suggests direct tyrosinase inhibition by ethyl acetate extract of Garcinia mangostana.

Extract from plants have been reported to contain valuable bioactive compounds that have potential in promoting antioxidant activity. The present study was aimed to investigate the extracts of two plants available in Southeast Asia, Eurycoma longifolia and Swietenia macrophylla for their primary metabolite contents, phenolic contents, antioxidant and anti-tyrosinase activity. Two types of solvents were utilised in the extraction process of both plants. Ethyl acetate found to be a better solvent for isolation of primary metabolite compound compared to methanol. For Folin-Ciocalteu assay, methanol extract of Swietenia macrophylla possed higher phenolic content while for Eurycoma longifolia, ethyl acetate extract had higher phenolic content. In DPPH assay, the radical scavenging activity of extracts were strongly correlated to the total phenolic content based on the percentage of DPPH radical scavenging of each extracts (p<0.05). In tyrosinase inhibition assay, the activity of each extracts were very low compared to standard Kojic acid. It was assumed that, the ability of plant extracts to inhibit tyrosinase are partly contributed by antioxidant potential of the extracts (p<0.01).

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This study aims to demonstrate the formation of aerobic granular sludge (AGS) for domestic wastewater treatment applications in hot climate and low humidity conditions (e.g. Saudi Arabia) as well as to characterize and examine the bioreactor performance in removing organic matter and nutrients. Based on the study, aerobic granular sludge (seeded with domestic activated sludge from Al-Madina Wastewater Treatment Plant and fed with synthetic wastewater with an organic loading rate (OLR) of 1.6 kg COD m−3d−1) was successfully cultivated with average size ranging from 1 to 2 mm in a laboratory scale sequencing batch reactor (SBR) system operated at 30 days with a complete cycle time of 3 h and at the working temperature of 30 ± 1°C. Results also showed that the aerobic granular sludge formed had excellent settling ability (settling velocity, 38.98 mh−1 and MLSS, 7.8 gL−1) and great removal performance of COD and nutrient (i.e. more than 90%).