In eyes that had had HSV keratitis, corneal sensitivity to mechanical forces and heat was significantly impaired, suggesting that axonal damage and/or altered expression of membrane ion channels involved in transduction and membrane excitability affects primarily the mechano- and polymodal nociceptor terminals. Corneal cold-sensitive terminals remain largely unaffected.
OFD as an immediate cause of FMVA began to play a role from the age of 60 years onwards. The role of health conditions as a cause of FMVA was higher than expected. Cardiovascular disease (70%) was found to be the leading medical condition that inhibited the driving task among the DA related to FMVA in Finland.
Central toxic keratopathy is not related to laser in situ keratomileusis (LASIK) only. The presence of 5 cases after PRK in a short period (2 months) associated with a period of simultaneous change of both postoperative medications and postoperative bandage lens practice suggests a link with an unknown pharmacological response leading to stromal dehydration.
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