ABSTRAKCandida. albicans (C.albicans) merupakan agen penyebab primer pada oral candidiasis. Candida spp merupakan mikroorganisme komensal atau ora normal dalam mulut dengan tanpa menimbulkan gejala. Candida spp dapat menjadi patogen saat kondisi daya tahan tubuh menurun terutama dalam kondisi penyakit autoimun yang diberikan terapi steroid karena steroid bersifat menurunkan sistem imun atau terapi obat-obatan secara sistemik dalam jangka waktu lama. Penelitian oral candidiasis di Indonesia masih belum banyak dilakukan. Penelitian ini bertujuan untuk mengetahui pro l oral candidiasis pada pasien-pasien yang ditangani di Bagian Penyakit Mulut di Rumah Sakit dr. Hasan Sadikin (RSHS), Bandung, Indonesia periode tahun 2010 -2014. Hasil penelitian menunjukkan selama periode 2010 hingga 2014 sebanyak 49 orang pasien yang datang ke klinik ilmu penyakit mulut ditemukan oral candidiasis. Prevalensi terbanyak adalah pria sebesar 34 orang (69,3%) dan wanita 15 orang (30,7%), dengan faktor predisposisi terbanyak adalah keterlibatan penyakit sistemik sebesar 40,2%. Lokasi paling sering ditemukan lesi plak pseudomembran putih dan terdapat di daerah dorsal lidah. Pro l kandidiasis pada pasien yang berkunjung ke klinik ilmu penyakit mulut RSHS secara garis besar umumnya disebabkan oleh kondisi sistemik, penyakit autoimun dan kebersihan rongga mulut yang buruk sedangkan untuk terapi kandidiasis, penggunaan nystatin masih efektif untuk digunakan mengobati kandidiasis. RSHS Bandung, Indonesia at 2010 -2014
Kesehatan gigi Ibu hamil sangat perlu dijaga, untuk menghindarkan terjadinya infeksi pada gigi dan gusi. Upaya ini akan menghindarkan dari infeksi yang berisiko yang menyebabkan prematur dan kelahiran berat bayi lahir rendah. Tujuan penelitian untuk mengetahui pengalaman karies dan kesehatan periodontal dan kebutuhan perawatan ibu hamil. Metode: Metode penelitian yang digunakan deskriptif. Populasi penelitian adalah ibu hamil yang datang ke Klinik Cantik Banjaran Bandung. Sampel penelitian yaitu ibu hamil yang bersedia menjadi subjek penelitian dan tidak mempunyai kelainan sistemik. Teknik pengambilan sampel adalah convinience sampling. Variabel penelitian pengalaman karies diukur dengan indeks DMFT, Kebutuhan perawatan karies adalah perhitungan kebutuhan perawatan berdasarkan penilaian persen kebutuhan perawatan dan kebutuhan perawatan periodontal diukur dengan indeks Community Periodontal Index and Treatment Needs (CPITN). Analisis data yang digunakan adalah distribusi frekuensi relatif. Hasil: Indeks DMFT ibu hamil 4,4 termasuk kriteria sangat rendah. Hasil CPITN yaitu periodontal sehat 0%; bleeding on probing (BOP), 43%; kalkulus, 53%; poket 4-5 mm, 3,3%; poket 6 mm, 0%. Kebutuhan perawatan gigi berlubang pada ibu hamil 30,9%. Kebutuhan perawatan jaringan periodontal diperlukan pada semua ibu hamil, berupa perbaikan oral hygiene 43%, perbaikan oral hygiene dan skeling 56%, Simpulan: Pengalaman karies ibu hamil pada kriteria sangat rendah, sedangkan kondisi jaringan periodontal ibu hamil semuanya memerlukan perawatan jaringan periodontal tetapi bukan perawatan periodontal kompleks. Kata kunci: Ibu hamil, indeks DMFT, indeks CPITN Caries experience, periodontal health, and oral treatment needs of pregnant women ABSTRACT Introduction: The oral health of pregnant women needs to be maintained to avoid infection of the teeth and gums. This effort will avoid dangerous infections that can cause premature and low birth weight babies. The purpose of this study was to determine the caries experience, periodontal health, and the oral treatment needs of pregnant women. Methods: The research method was descriptive. The study population was pregnant women who came to the Cantik Clinic of Banjaran, Bandung, whom willing to be the subject of research with no systemic abnormalities. The sampling technique was convenience sampling. The caries experience was measured by DMFT index. Caries treatment needs were the calculation of treatment needs based on the assessment of general and periodontal treatment needs to be measured by the Community Periodontal Index and Treatment Needs (CPITN) index. Data analysis used was the relative frequency distribution. Result: DMFT index of pregnant women was 4.4, included in the very low criteria. CPITN index measurement results were 0% healthy periodontal; 43% bleeding on probing (BOP); 53% calculus; 3.3% pocket of 4-5 mm; and 0% 6 mm pocket. General treatment needs of pregnant women mostly were tooth decay treatment (30.9%). Periodontal treatment needs were needed for all pregnant women, in th...
Pendahuluan: Stomatitis Aftosa Rekuren (SAR) merupakan penyakit mulut yang sangat sering terjadi pada masyarakat. SAR memiliki gambaran klinis berupa lesi ulserasi kecil berbentuk bulat atau oval dengan tepi kemerahan dan batas yang jelas serta dasar ulser berwarna putih atau kekuningan. Prevalensi SAR pada populasi dunia bervariasi antara 5% sampai 66% dengan rata-rata 20%. SAR diklasifikasikan dalam 3 tipe yaitu lesi minor, mayor, dan herpetiform; lesi sering ditemukan di mukosa labial, biasa diberikan terapi farmakologi berupa anti inflamasi topikal, serta membutuhkan masa penyembuhan 7-10 hari. Tujuan penelitian ini adalah mengetahui profil lesi SAR pada pasien di Instalasi Ilmu Penyakit Mulut Rumah Sakit Gigi dan Mulut Universitas Padjadjaran (RSGM Unpad) periode tahun 2014-2015. Metode: Jenis penelitian yang dilakukan bersifat deskriptif dari penelusuran data sekunder. Sampel penelitian yaitu rekam medis pasien dengan diagnosa SAR di RSGM Unpad periode 2014-2015. Hasil: Kasus SAR ditemukan sejumlah 47 kasus dari sejumlah 132 keseluruhan kasus penyakit mulut di instalasi penyakit mulut RSGM Unpad periode 2014-2015. SAR sebagian besar terjadi pada pasien dengan jenis kelamin perempuan daripada laki-laki, serta paling banyak ditemukan pada usia 20-29 tahun. Simpulan: Profil lesi SAR lebih banyak ditemukan tipe SAR minor, berlokasi di mukosa labial, dengan lama penyembuhan 7-14 hari dan penatalaksanaan farmakologi yang paling sering diberikan adalah topikal anti inflamasi kortikosteroid.Kata Kunci : Profil lesi oral, stomatitis aftosa rekuren, ilmu penyakit mulut
Objective: To evaluate the safety of a pomegranate seeds ethanolic extract in Swiss webster mice. Material and Methods: Pomegranate seed's ethanolic extracts were evaluated for minimum inhibitory concentration against streptococcus sanguis ATCC 10556, using microdilution method through 96-wells microplate. In acute toxicity test, 12 females and 12 males Swiss Webster mice weighing 20-30 grams were divided into four groups, each consisting of 3 females and 3 males. Three groups were orally given of sample with concentrations 0.2% equivalent to 40 mg/kg, 0.4% equivalent to 80 mg/kg, and 0.8% equivalent to 160 mg/kg, while the control group was given distilled water. Observations were made at 30, 60 and 90 minutes, for 24 hours and 7 days. Results: The MIC against streptococcus sanguis was on 2000 ppm concentration and until 24 hours observation no lethal effect occurred on the mice, but at the 7 days observation in the group of 0.8% per kilogram body weight, the lethal effect occurred at one mice. Conclusion:The ethanolic extract of pomegranate seeds has antibacterial effect and no acute systemic toxicity, which can be considered safe on the use as oral topical solution since the toxic dose is greater than 160 mg/kg of body weight.Keywords: Pomegranate, Ethanolic extract, Acute systemic toxicity Cite this Article: Setiadhi, R., Sufiawati, I., Zakiawati, D., Nur'aeny, N., Hidayat, W., Firman, D.R. 2017. Evaluation of antibacterial activity and acute toxicity of pomegranate (punica granatum l.) seed ethanolic extracts in swiss webster mice.
Posyandu is the one of community-based health form which is had source and managed from, by, for the community in implementing health development. The purpose of community service activities (PPM / KKN) is that posyandu cadres are expected to receive health information and education regarding the introduction of various types of oral ulcers and knowledge about nutrition. Information presented in the form of counseling seminars and discussions that were previously shared by pre and post questionnaires as an indicator to see the effects of education carried out on public health cadres so that people are expected to get additional knowledge about health. A total of 50 posyandu cadres were given health education, from the results of the pre and post there was a considerable increase in health knowledge for cadres.PPM / KKN activities in the form of health counseling can be carried out consistently to maintain cadre knowledge about health so that by increasing the knowledge of health cadres, it is expected to increase the preventive health efforts of the oral cavity for the community, one of which is maintaining healthy oral cavity.
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