Human cytomegalovirus is a widespread herpesvirus that infects the vast majority of individuals. HCMV can establish long life latency. HCMV reactivations were reported in immunocompromised patients and pregnant females. HCMV causes congenital infections. In this study, almost 206 adults were underwent anti-HCMV IgG & IgM antibodies tests in Taiz International laboratory in Taiz city, Yemen (from March 2019 to December 2020). A total of 206 adults underwent HCMV antibodies screening tests. Among them, 12 males and 194 females. All males were HCMV IgG seropositive, while 97.9% of females were HCMV IgG seropositive. Among all patients, only four were HCMV IgM seropositive. All four HCMV IgM seropositive patients were HCMV IgG seropositive. Low socioeconomic status and poor hygiene practices determine HCMV prevalence in developing countries. Minister of Public Health, Yemen have to approve HCMV serologic test as a routine screening test for pregnant females to prevent HCMV neurological disorders in fetus/newborn.
The human cytomegalovirus (HCMV) is a common herpesvirus that affects nearly everyone. HCMV is a large an enveloped double-stranded DNA virus that belongs to the betaerpesvirinae subfamily. HCMV can be transmitted horizontally through the secretion of body or body fluids from person to person, or vertically from mother to child during primary infection. In this study, two hundred samples were collected from pregnant females that were visited three of obstetrics and gynecology clinics in Taiz city. Their ages ranged between (16-45) years. Samples were examined by using anti HCMV IgG ELISA kit. Anti-HCMV IgG positivity was found in 196 of the 200 (98%) of pregnant females tested, while only four of pregnant females were negative for anti-HCMV IgG antibodies. The highest rate of anti-HCMV IgG seropositivity was found among 31-35 and 41-45 age groups. 100% of third trimester pregnant females were seropositive to anti-HCMV IgG, while abortion was reported in 98.18% of seropositive pregnant females. Highest seroprevalence was among unemployed and non-educated females. Both females at urban and rural area are at risk of HCMV infection. The current study found a very high seroprevalence of anti-HCMV IgG antibody among Yemeni pregnant women in Taiz city. The good sanitation, proper diagnosis, education, and the development of vaccines and antiviral therapies may all aid in the control of HCMV-related congenital infection.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.