Seroprevalence of Human cytomegalovirus among adult Population in Taiz city, Yemen

Abstract

Human cytomegalovirus is a widespread herpesvirus that infects the vast majority of individuals. HCMV can establish long life latency. HCMV reactivations were reported in immunocompromised patients and pregnant females. HCMV causes congenital infections. In this study, almost 206 adults were underwent anti-HCMV IgG & IgM antibodies tests in Taiz International laboratory in Taiz city, Yemen (from March 2019 to December 2020). A total of 206 adults underwent HCMV antibodies screening tests. Among them, 12 males and 194 females. All males were HCMV IgG seropositive, while 97.9% of females were HCMV IgG seropositive. Among all patients, only four were HCMV IgM seropositive. All four HCMV IgM seropositive patients were HCMV IgG seropositive. Low socioeconomic status and poor hygiene practices determine HCMV prevalence in developing countries. Minister of Public Health, Yemen have to approve HCMV serologic test as a routine screening test for pregnant females to prevent HCMV neurological disorders in fetus/newborn.