Our study suggests that the analysed genetic polymorphisms of cytokine genes do not appear to be associated with AD susceptibility in our Chinese population.

4 Kroeger KM, Carville KS, Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 1997; 34: 391-399. 5 Javor J, Bucova M, Ferencik S, Grosse-Wilde H, Buc M. Single nucleotide polymorphisms of cytokine genes in the healthy Slovak population. Int J Immunogenet 2007; 34: 273-280. 6 Paraskevaidis A, Drakoulis N, Roots I et al. Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne. Dermatology 1998; 196: 171-175. 7 Sobjanek M, Zablotna M, Sokolowska-Wojdylo M. Polymorphism in cytochrome P-450 (CYP1A1) in acne vulgaris: preliminary study. Post Dermatol Alergol 2007; 24: 69-72. 8 He L, Yang Z, Yu H et al. The relationship between CYP17 -34T/C polymorphism and acne in Chinese subjects revealed by sequencing. EditorA 45-year-old man presented with a complaint of a 4-month history of two progressively enlarging skin tumours, one each on the occipital scalp and nape (Fig. 1a,b). Initially, the scalp lesion began first, and the nape lesion developed a few days later. Multiple enlarged lymph nodes could be palpated in the neck and supraclavicular area. Incisional biopsies of both lesions were