HELLP syndrome is a severe complication of preeclampsia, incalculable in its course and involving high risk for mother and fetus. Over a period of three years and eight months a total of 24 patients with HELLP syndrome were treated at Göttingen University Gynecological Clinic and the Gynecological Clinic of Munich Technical University. In all cases the correct diagnosis had already been made by the referring physician or by the obstetrician on admission, taking laboratory parameters into account. The chief clinical symptom was upper abdominal pain, All of the patients presented with thrombocytopenia and elevated liver enzymes. The signs of hemolysis derived from the increased bilirubin concentrations and the LDH; in 13 cases fragmentocytes were detected in the peripheral blood smear. No indications of a pronounced DIG were found. The mean time elapsed between hospitalization and delivery was six hours (0.5-40 hours); 22 patients were delivered within 24 hours. Cesarean section was performed in all cases. The mean gestational age at the time of birth was 35 weeks (25-38). Three of 24 children died prepartially; with the surviving infants no major problems arose in the postnatal course. In 19 cases the abdominal cesarean delivery and clinical course were without complications. Reoperation, in two cases combined with a puerperal hysterectomy, was necessary in three patients, due to subfascial and intraperitoneal or retroperitoneal hematomas.(ABSTRACT TRUNCATED AT 250 WORDS)
Despite the fact, that acute pseudo-obstruction of the colon (Ogilvie's syndrome) is a rare entity, many of the reported cases have occurred after gynaecologic and obstetric surgical procedures. In order to avoid life-threatening complications, such as caecal perforation, early detection and initiation of conservative treatment is necessary. We report on three cases with Ogilvie's syndrome after caesarean section. Symptoms and treatment are discussed.
Using a review of the literature and own data, the paper describes the methods of obstetrical Doppler sonography, its technical development and its clinical application. The safety standards, physiological changes in vascular resistance and the clinical use of this new method were discussed and compared with the conventional methods. The technical perspective of the method seems to lie with the color flow duplex scanner and the possibility of computerized on-line evaluation. Clinically the method seems to be useful in the early detection of the hypoxic fetus. The Doppler sonography is assessed as an additive but valuable method.
During an eight year period, 100 patients with the diagnosis of pre-eclampsia and HELLP syndrome were treated at the Departments of Obstetrics and Gynaecology of 2 University Hospitals (Technische Universität München and Universität Göttingen). The clinical treatment concepts, which were used in common at the two hospitals, are presented and differ from the common clinical management of pre-eclampsia. The results and therapy concepts are compared and critically reviewed. In recent years, the number of diagnoses and cases of HELLP syndrome has been increasing. Case reports, epidemiological statistics and maternal and perinatal mortality rates indicate a change of the "Gestalt" of preeclampsia due to the HELLP syndrome and its complications.
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