What are the novel findings of this work? Body mass index (BMI) and a history of pre-eclampsia have an independent effect on vascular health. The effects of pre-eclampsia and BMI on insulin resistance appear to be synergistic. Independently of BMI, a history of pre-eclampsia has a detrimental impact on carotid intima-media thickness, carotid distensibility and blood pressure.
What are the clinical implications of this work?Recognizing the cardiovascular risk profile is important for informing patients and promoting targeted and tailor-made lifestyle interventions. Insulin resistance appears to have an important pathophysiological effect on vascular health in women with a history of pre-eclampsia.
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