Between 1979 and 1984, 43 Neer total shoulder arthroplastics were performed on 38 patients with polyarthritis in the University Department of Orthopaedic Surgery, Glasgow ; one patient died of unrelated causes within six months of surgery and has been excluded from the study.
Following periods of 1 or 3 1/2 hours of haemorrhagic shock in 12 anaesthetized ventilated greyhounds, ultrafiltrates of plasma taken 4 hours after retransfusion exibited significantly increased depressant activity on guinea‐pig atrium in vitro. This effect was significantly greater following prolonged hypotension and could not be accounted for by changes in electrolyte composition. It is suggested that this effect may be related to defective myocardial function following haemorrhagic shock.
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