Ethane-2-chloro-l-hydroxy-l, 1-diphosphonic acid is readily dehydrohalogenated on treatment with aqueous base. The rate of chloride loss displays a first-order dependency tin the concentration of the parent diphosphonate, and is greatly influenced by the degree of neutralization of the parent acid. The product isolated after all chloride has been removed is Na203PCH2C (0 )P03Na2, wherein one of the geminal phosphonate groups has undergone a 1,2 shift. This structure is deduced from 31P, , and 13C nmr spectra, and is consistent with ir and uv spectral patterns. Stabilities of various acid and salt forms of this new carbonyl phosphonate are discussed and its conversion to ethane-1-hydroxy-1,1,2-triphosphonic acid via addition to the carbonyl group is demonstrated.
Aus Chloressigsäure (I) und dem Phosphoroxid (II) entsteht die Äthan‐2‐chlorl‐hydroxy‐1,1‐diphosphonsäure (III), die mit ausreichenden Mengen an Alkali in das Anion (IVa) übergeführt wird.
Aus den Alkinolen (I) und dem Phosphit (II) entstehen in Gegenwart von Natrium die vicinalen Polyphosphonate (III) (72% Ausbeute), aus denen durch saure Hydrolyse die Titelverbindungen dargestellt werden.
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