Background: Periorbital wrinkle formation is a relatively early sign of skin aging. The public interest in the reversal of aging has increased significantly among demanding patients and aesthetic practitioners within the past decades. However, many aesthetic patients, whether young or old, prefer to avoid invasive procedures wherever possible, seeking natural-looking results.Therefore, physicians have had to respond to their patient's expectations. Objectives: This study aimed to evaluate whether the synergistic anti-aging activity of MF3 Placenta 3R serum product has an influence towards the treating of wrinkles as well as skin hydration, and skin elasticity in the periorbital area. Methods: 23 healthy adult female volunteers were instructed to apply MF3 Placenta 3R serum containing a mixture of low molecular weight hyaluronic acid (LMWHA), placental peptides and extract of Malus domestica around the eye area twice daily during the study period of eight weeks. The skin measurements were performed in the periorbital area by investigating the skin elasticity (Cutometer) and skin hydration (Corneometer). Patients questionnaires were answered at 59 days. Results: The findings of the study proved a moisturizing impact of MF3 Placenta 3R serum throughout the trial that transformed into significant improvements in periocular skin hydration and elasticity. Conclusion: The tested formulation of MF3 Placenta 3R serum appears to be effective and may stimulate the periorbital skin rejuvenation in a women 44 – 52 years, resulting in the clinical appearance of smoother skin with less visible wrinkling. Further randomized, controlled studies have to be done to confirm these results.
The structural composition of the skin is dynamic, exhibiting various signs of aging such as the decrease in collagen and elastin content leading to increase in tactile and visual roughness, dryness, wrinkles, fine lines and stiffness as age advances. This study was done to elicit the efficacy and potency of mesotherapy using a cocktail of triple strength nano-sized peptides from the skin, placenta, mesenchyme fortified with collagen and hyaluronic acid (HA) in the revitalisation of the skin of the dorsum of the hand. Ten male subjects suffering from mild signs of aging of the skin were treated with the formulation of MF+ SPMC + HA over the dorsum of both hands. The treatment course spanned over eight weeks with once a week application. Baseline assessment was done before the treatment and at the end of the first and second month and 90 days post-therapy, respectively, using photography, ultrasound comparison and biophysical parameters of the skin. The results proved the application of SPMC + HA rendered long-term hydration and improved the viscoelasticity of the treated area. The study concluded that mesotherapy application of MF+ SPMC extracts/peptides in combination with hyaluronic acid could be considered as a safe and effective method for rejuvenation of the skin of the dorsum of hands.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.