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Quinoxaline derivatives seem to have very interesting biological properties (1-3). The plant alkaloid ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole) has DNA-intercalating and antitumor activity and is active against the herpes simplex virus (4, 5). Graslund et al. (6) have studied ellipticine and the derivatives 2,3-dimethyl-6-(2-dimethyl-aminoethyl)6H-indolo[2,3-b]quinoxaline and 6-(2-dimethylaminoethyl)6H-indolo [2,3-b] quinoxaline for their interaction with oligodeoxynucleotide duplexes. They reported that compounds were intercalated in a non-specific fashion and by an AT-specific interaction.Recently, Sauvain et al. (7) reported that 3-(4'-chloro)phenylquinoxaline-2-carbonitrile-1,4-di-N-oxide had potent antimalarial activity particularly against a chloroquine--resistant strain of Plasmodium falciparum. Moarbess et al. (8) Various 6-aralkyl-9-substituted-6H-indolo[2,3-b]quinoxalines were synthesized by reaction of 1,5-disubstituted 2,3-dioxo-2,3-dihydroindole and orthophenylene diamine. Appreciable anticancer activity of compounds 5b, 5d, 5g and 5l at various cell lines among 59 human tumor cell panels was observed. All the synthesized compounds were evaluated for cytostatic activity against human Molt 4/C8 and CEM T-lymphocytes as well as for murine L1210 leukemia cells. Compound 5h exhibited an IC 50 of 23 mmol L -1 against Molt 4/C8 and 38 mmol L -1 against CEM compared to melphalan 3.2 mmol L -1 and 2.5 mmol L -1 , respectively. The IC 50 for compound 7i against L1210 was 7.2 mmol L -1 compared to melphalan 2.1 mmol L -1 .

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Starch is extracted from the seeds of a pigmented (Phule Rohini) and a non‐pigmented (Phule Maldandi) Indian sorghum cultivar using same wet milling method for both cultivars. This study is focused on investigation of the effect of the pigment on starch characteristics. Isolated starches differing in color are irradiated with an electron beam dose of 5 kGy and compared by measuring physicochemical, structural, pasting, and digestibility properties. Amylose content increases after irradiation and the increase is greater in the case of Phule Maldandi starch. The pigmented starch shows higher carboxyl content after irradiation which may be due to higher amylopectin content. Granular morphology remains constant after irradiation. Irradiation causes a decrease in swelling power and an increase in pasting viscosity of both starches. Color content of red sorghum starch is not changed significantly after irradiation. The increase in pasting viscosity and solubility of non‐pigmented starch is more drastic in nonpigmented starch than in pigmented starch after irradiation. Resistant starch decreases after irradiation which indicates opening up of granular structure or hydrolytic action of irradiation. Pigmented starch can have potential applications in custard powder and bakery products.

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