Personalized medication (PM) is a wide and progressed field of medical science with more accuracy of medication to educate every individual’s clinical data. This model categorizes individuals within discrete subject groups with medical accountability, utility, or products being customized to each group based on their expected response. It is an emergent and rapidly developing method of clinical practice which utilizes advanced technologies that give a conclusion concerning to the prognosis, prevention, recognition, and treatment of diseases. The advantages is to improve the usefulness of PM over traditionally approved drugs due to less toxicity and side effect with therapeutic efficacy, which leads to patient stratification, proactive treatment regimens resulting in reduced health-care costs, and ultimately enhanced the quality of life. This review focused to an extensive understanding of personalized medicines as a major therapeutic approach to overpass the health-care problems and highlights the challenges, current strategies, and future prospective.
Objectives: In this work, the photo components were investigated utilising GC-MS analysis and in vitro antioxidant activity, and the anthelmintic potential of methanolic extract of aerial parts of the Lagenaria siceraria (MEALS). By using the soxhlation method. Materials and Methods: MEALS were made from aerial components, and phytochemical analysis was carried out for a qualitative evaluation. The in vitro antioxidant activity was measured using the ABTS technique, and the current extract was utilised to analyse phytocomponents by GC-MS and study anthelmintic activity on Pheretima posthuma. The extract of Lagenaria siceraria included 59 components, according to the GC-MS study's phytochemical analysis. Results: Results from anthelmintic research reveal that MEALS had paralysis times between 4.76 and 2.17 min and death times between 6.18 and 2.34 min when compared to the medicine Albendazole, which is the gold standard (paralysis time 4.76 min to 2.17 min and death time 5.87 min to 1.96 min on Peritima posthuma in increasing order of concentration). The percentage of scavenging ranged from 33.31% to 82.33% (IC 50 143) and by standard medicine (ascorbic acid) from 49.47% to 94.73% (IC 50 103) using the ABTS technique in the evaluation of an antioxidant activity. Conclusion: Due to the presence of physiologically active phytocomponents, aerial sections of the Lagenaria siceraria (MEALS) were shown to be potent anthelmintic and antioxidant agents.
The COVID-19 pandemic has wreaked havoc on education systems around the world, affecting approximately 1.7 billion students in over 200 nations. More than 95% of the world’s student population has been touched by school, institution, and other learning facility closures. This has resulted in significant changes in every part of our life. Traditional educational techniques have been considerably disrupted by social alienation and limited movement policies. The reopening of schools once the restrictions have been lifted is another challenge, as many new standard operating procedures have been implemented. Many scholars have shared their work on teaching and learning in various ways in the aftermath of the COVID-19 outbreak. Face-to-face instruction has been phased out at a number of schools, colleges, and universities. There is concern that the 2020 academic year, or maybe more in the future, would be lost. Innovation and implementation of alternative educational systems and assessment methodologies are urgently needed. The COVID-19 epidemic has given us the opportunity to lay the groundwork for digital learning. The purpose of this article is to present a complete assessment on the influence of the COVID-19 epidemic on online teaching and learning of various papers, as well as to suggest a course of action and future aspects.
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