The study aimed to evaluate the nature and extent of executive deficits in nondemented amyotrophic lateral sclerosis (ALS) patients. A total of 22 ALS patients and 21 matched controls were compared on standard neuropsychological tests of executive functions with appropriate control for motor impairment and on an ecologically valid motor-free test of executive functions, the Medication Scheduling Task (MST). Our results show that motor dysfunction can present a significant confound when using standard neuropsychological measures; however, even when accounting for motor disabilities, ALS patients show a robust pattern of cognitive dysfunctions. Additionally, MST was shown to be a sensitive measure of cognitive impairment, providing an important insight into cognitive processes relevant for patients' daily living.
Providing continuous coverage of key services, shift work is a necessity of the modern world. It varies according to the number and length of the shifts and according to scheduling patterns. However, it is common to all forms that they ensure the smooth running of a particular service with the 24-hour presence of staff. This means that working time partly or completely overlaps with night sleep, causing an imbalance between circadian rhythms and the requirements of the environment. Aforesaid imbalance has a negative effect on sleep and can lead to sleep disorders, which in turn cause mental health problems. In addition, the development of unhealthy behaviours developed by shift workers to manage their working hours (especially night work) and the inconsistency of their working hours with those of the general population also lead to poorer mental health, lower quality of social life and family conflicts. However, since shift work cannot be completely eliminated, it is necessary to consider designing the measures to reduce the negative impact of shift work on the mental health and well-being of workers, both at the individual level, as well as at the level of working organisations. Some of the key measures are presented in the article.
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