The ligature model was an effective approach to induce inflammation and bone loss similar to human periodontitis, but the oral gavage models were not efficient in inducing periodontal inflammation and tissue destruction in the conditions studied. Ligature models can provide a basis for future interventional studies that contribute to the understanding of the disease pathogenesis and the complex host response to microbial challenge.
Odontogenic cysts are considered as nonneoplasic benign lesions. Among the cysts, keratocyst odontogenic tumor (KCOT) is an intra-osseous tumor characterized by parakeratinized stratified squamous epithelium and a potential for aggressive, infiltrative behavior, and for the possibility to develop carcinomas in the lesion wall. Thus, the aim of this study was to describe a clinical case of KCOT in a young patient and discuss the treatment alternatives to solve this case. A 15-year-old male was referred for treatment of a giant lesion in his left side of the mandible. After the biopsy, a diagnostic of KCOT was made, and the following procedures were planned for KCOT treatment. Marsupialization was performed for lesion decompression and consequent lesion size reduction. Afterward, enucleation for complete KCOT removal was performed followed by third mandibular molar extraction. After 5 years, no signs of recurrence were observed. The treatment proposed was efficient in removing the KCOT with minimal surgical morbidity and optimal healing process, and the first and second mandibular molars were preserved with pulp vitality. In conclusion, this treatment protocol was an effective and conservative approach for the management of the KCOT, enabling the reduction of the initial lesion, the preservation of anatomical structures and teeth, allowing quicker return to function. No signs of recurrence after 5 years were observed.
INTRODUÇÃO: O baixo peso de recém-nascidos (RN) é considerado um problema de saúde pública e, geralmente, é associado à prematuridade. A etiologia do parto prematuro é bastante complexa e, frequentemente, está relacionada a vários fatores. Diversas teorias têm correlacionado a saúde periodontal de gestantes com o nascimento de bebês prematuros (idade gestacional) e/ou com baixo peso ao nascer. OBJETIVO: O objetivo do presente estudo foi avaliar a possível correlação de saúde periodontal com idade gestacional e/ou com nascimento de bebês com baixo peso. MATERIAL E MÉTODO: Estudo observacional longitudinal prospectivo com gestantes que foram atendidas em um projeto de extensão da Universidade Federal do Piauí - Programa Preventivo para Gestantes e Bebês - PPGB. A coleta dos dados foi estruturada em dois momentos: 1º- Preenchimento de ficha contendo dados relativos à saúde geral e exame periodontal completo, e 2º- Coleta de dados referentes a tipo de parto, duração da gestação, peso e condição de saúde do bebê. RESULTADO: De 62 gestantes atendidas, 43 participaram do segundo momento do estudo. Ocorreu uma predominância de gestantes com idade entre 25 e 35 anos (55,81%). O índice de sangramento gengival variou de 1,19% a 92,50%. A média do peso dos bebês foi 3.365,33 g e do tempo gestacional foi 39,33 semanas. CONCLUSÃO: Os resultados deste estudo não deram suporte à hipótese de que a doença periodontal está associada à idade gestacional.
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