In this work we aim to synthesize biocompatible ZnO nanoparticles from the zinc nitrate via green process using leaf extracts of the Costus pictus D. Don medicinal plant. FTIR studies confirm the presence of biomolecules and metal oxides. X-ray diffraction (XRD) structural analysis reveals the formation of pure hexagonal phase structures of ZnO nanoparticles. The surface morphologies of ZnO nanoparticles observed under a scanning electron microscope (SEM) suggest that most ZnO crystallites are hexagonal. EDX analysis confirms the presence of primarily zinc and oxygen. TEM images show that biosynthesized zinc oxide nanoparticles are hexagonal and spherical. The plausible formation mechanisms of zinc oxide nanoparticles are also predicted. The biosynthesized zinc oxide nanoparticles exhibit strong antimicrobial behavior against bacterial and fungal species when employing the agar diffusion method. Synthesized ZnO nanoparticles exhibit anticancer activity against Daltons lymphoma ascites (DLA) cells as well as antimicrobial activity against some bacterial and fungal strains.
Exactly about 0.1 M of AgNO 3 was dissolved in50 mL of doubledistilled water along with10 mL of Cyathea nilgiriensis aqueous extract under under magnetic stirring at 80°C for 4 hr. The complex formed was ultracentrifuged at 10,000 rpm for 10 min, rinsed with water and further
Plant secondary metabolites play a major role in biosynthesis of nanoparticles. As a new approach, we have used aqueous ethanolic extract of Cyathea nilgirensis Holttum to synthesize MgO nanoparticles by chemical precipitation method. FT-IR spectroscopy studies have proved that biomolecules have acted as stabilizing agents in the synthesis of MgO nanoparticle. SEM analysis has exhibited the morphological appearance of MgO nanoparticles. Energy Dispersive X-Ray analysis has proved the presence of both magnesium and oxygen in the synthesized MgO nanoparticles. The fungal species A. niger is observed to have remarkably higher percentage of inhibition (71.4%). The results of cancer studies suggest that as concentration increases from 10 μg to 200 μg, the percentage of inhibition of MgO nanoparticles increases. Thus plant extract mediated MgO nanoparticles have proven to be a better antimicrobial and anticancer agent.
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